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82467-52-5

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82467-52-5 Usage

Description

Isokadsuranin is a Schisandrin B enantiomer found in rat plasma, characterized by its multiple pharmacological properties.

Uses

Used in Pharmaceutical Industry:
Isokadsuranin is used as a pharmaceutical agent for its diverse pharmacological properties, which include potential applications in various therapeutic areas.
Used in Drug Development:
Isokadsuranin is utilized in drug development as a compound with multiple pharmacological properties, offering a promising foundation for the creation of new medications targeting a range of health conditions.

Check Digit Verification of cas no

The CAS Registry Mumber 82467-52-5 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 8,2,4,6 and 7 respectively; the second part has 2 digits, 5 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 82467-52:
(7*8)+(6*2)+(5*4)+(4*6)+(3*7)+(2*5)+(1*2)=145
145 % 10 = 5
So 82467-52-5 is a valid CAS Registry Number.

82467-52-5SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 20, 2017

Revision Date: Aug 20, 2017

1.Identification

1.1 GHS Product identifier

Product name Benzo[3,4]cycloocta[1,2-f][1,3]benzodioxole, 5,6,7,8-tetrahydro-1,2,3,13-tetramethoxy-6,7-dimethyl-, (6R,7S,13aR)-

1.2 Other means of identification

Product number -
Other names (+)--Schisandrin B

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:82467-52-5 SDS

82467-52-5Relevant articles and documents

Biotransformation of isofraxetin-6-O-β-D-glucopyranoside by Angelica sinensis (Oliv.) Diels callus

Zhou, Di,Zhang, Yuhua,Jiang, Zhe,Hou, Yue,Jiao, Kun,Yan, Chunyan,Li, Ning

, p. 248 - 253 (2016/12/27)

Isofraxetin-6-O-β-D-glucopyranoside, identified from traditional medicinal herbal Xanthoceras sorbifolia Bunge, has been demonstrated to be a natural neuroinflammatory inhibitor. In order to obtain more derivatives with potential anti-neuroinflammatory effects, biotransformation was carried out. According to the characteristics of coumarin skeleton, suspension cultures of Angelica sinensis (Oliv.) Diels callus (A. sinensis callus) were employed because of the presence of diverse phenylpropanoids biosynthetic enzymes. As a result, 15 products were yielded from the suspension cultures, including a new coumarin: 8′-dehydroxymethyl cleomiscosin A (1), together with 14 known compounds. Their structures were elucidated by extensive spectroscopic analysis. Furthermore, the biotransformed pathways were discussed. Among them, compound 13 was transformed from isofraxetin-6-O-β-D-glucopyranoside, while compounds 1–6, 10–12, 14–15 were derived from the culture medium stimulated by the substrate. The biotransformation processes include hydroxylation, oxidation and esterification. Furthermore, their inhibitory effects on lipopolysaccharide (LPS)-activated nitric oxide (NO) production were evaluated in BV2 microglial cells. It is worth noting that, 1, 1′-methanediylbis(4-methoxybenzene) (3), obtucarbamates A (5), 2-nonyl-4-hydroxyquinoline N-oxide (10) and 1H-indole-3-carbaldehyde (11) exhibited significant inhibitory effect against neuroinflammation with IC50values at 1.22, 10.57, 1.02 and 0.76?μM respectively, much stronger than that of the positive control minocycline (IC5035.82?μM).

Kadsulignans L-N, three dibenzocyclooctadiene lignans from Kadsura coccinea

Liu Jia-Sen,Li Liang

, p. 241 - 245 (2007/10/02)

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The constituents of Schizandra chinensis BAILL. X. The structures of γ-schizandrin and four new lignans, (-)-gomisins L1 and L2, (±)-gomisin M1 and (+)-gomisin M2

Ikeya,Taguchi,Yosioka

, p. 132 - 139 (2007/10/02)

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