82467-88-7Relevant academic research and scientific papers
Synthesis of 3-keto-4-diazo-5-α-dihydrosteroids as potential irreversible inhibitors of steroid 5-α-reductase
Metcalf, Brian W.,Jund, Karin,Burkhart, Joseph P.
, p. 15 - 18 (2007/10/02)
3-Keto-4-diazo-5-α-dihydrosteroids are prepared using the Hendrickson diazo transfer reaction on the corresponding β-diketones, which are available from 3-ketoΔ-4-steroids via Li/NH3 reduction and acylation of the kinetic enolate.
