82475-01-2 Usage
Description
Oroxylin A 7-O-beta-D-glucuronide methyl ester is a flavonoid derivative isolated from the herb Scutellaria baicalensis, commonly known as Chinese skullcap. It possesses potential anti-inflammatory and anticancer properties, making it a promising candidate for natural medicine and drug development.
Uses
Used in Pharmaceutical Industry:
Oroxylin A 7-O-beta-D-glucuronide methyl ester is used as an anti-inflammatory agent for its ability to reduce inflammation by targeting specific signaling pathways in the body.
Used in Oncology:
Oroxylin A 7-O-beta-D-glucuronide methyl ester is used as an anticancer agent for its potential to inhibit the growth of cancer cells and modulate oncological signaling pathways, offering a promising alternative or adjunct to conventional cancer treatments.
Used in Antioxidant Applications:
Oroxylin A 7-O-beta-D-glucuronide methyl ester is used as an antioxidant for its ability to neutralize harmful free radicals and protect cells from oxidative damage, contributing to overall health and well-being.
Used in Neuroprotection:
Oroxylin A 7-O-beta-D-glucuronide methyl ester is used as a neuroprotective agent for its potential to protect neurons and support brain health, making it a candidate for further research in the treatment of neurodegenerative diseases.
Check Digit Verification of cas no
The CAS Registry Mumber 82475-01-2 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 8,2,4,7 and 5 respectively; the second part has 2 digits, 0 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 82475-01:
(7*8)+(6*2)+(5*4)+(4*7)+(3*5)+(2*0)+(1*1)=132
132 % 10 = 2
So 82475-01-2 is a valid CAS Registry Number.
82475-01-2Relevant articles and documents
An efficient, scalable approach to hydrolyze flavonoid glucuronides via activation of glycoside bond
Jiang, Xue-Yang,Li, Xin-Chen,Liu, Wen-Yuan,Xu, Yun-Hui,Feng, Feng,Qu, Wei
, p. 1895 - 1903 (2017)
Hydrolyzing flavonoid glucuronides into corresponding aglycones posed some significant challenges. To improve acid-catalyzed hydrolysis process of flavonoid glucuronide, structures of glucuronide, hydrolysis parameters and post-processing were optimized. The optimized condition was performed by hydrolysis flavonoid glycoside methyl ester in a mixed solvent consisting of 2?mol/L H2SO4/EtOH/H2O (1/8/1, v/v/v) at 95?°C for 7?h and resulted in up to 90% aglycone yields, minimal byproduct formations and milder hydrolysis conditions. Furthermore, the optimized method avoids tedious purification steps and is easily conducted on a relatively large-scale using economical and commercially available reagents.
