82495-84-9

Upstream product

• 1073-13-8 4,4-dimethylcyclohexenone 
• 118653-39-7 methyl 3,3-dimethyl-6-oxocyclohex-1-ene-1-carboxylate 
• 50388-51-7 methyl 5,5-dimethyl-2-oxo-cyclohexanecarboxylate 
• 4255-62-3 4,4-dimethylcyclohexane-1-one 

Downstream Products

• 82511-63-5 3(N),4-dibenzyl-8-(2'-trimethylsilyl)ethoxy-6,7,13,13-tetramethyl-2-oxo-3-aza-9-oxatricyclo<8.4.0.0^5,10>tetradeca-1,6-diene 
• 82522-07-4 (3S,3aR,6aS,7S,10aS)-3,3a,6,6a,7,8,9,10-octahydro-2,3-dibenzyl-7-(2'-trimethylsilyl)ethoxy-4,5,7,7-tetramethyl-1H-benzisoindole-1,10-dione 
• 74974-82-6 (3S,3aR,6aS,10aS)-3,3a,6,6a,7,8,9,10-octahydro-2,3-dibenzyl-4,5,7,7-tetramethyl-1H-benzisoindole-1,10-dione 
• 82495-85-0 (2'S)-3,3-dimethyl-6-oxocyclohex-1-enyl-1-((Z,E)-N,N-benzyl-2'-<6'-(trimethylsilyl)ethoxy-4',5'-dimethyl-1'-phenyl>hexa-3',5'-dienyl)carboxamide 
• 82495-86-1 (2'S)-3,3-dimethyl-6-oxocyclohex-1-enyl-1-((Z,Z)-N,N-benzyl-2'-<6'-(trimethylsilyl)ethoxy-4',5'-dimethyl-1'-phenyl>hexa-3',5'-dienyl)carboxamide 
• 74974-76-8 3,3-Dimethyl-6-oxo-cyclohex-1-enecarboxylic acid benzyl-((E)-(S)-1-benzyl-3,4-dimethyl-penta-2,4-dienyl)-amide 
• 74974-81-5 (2'S)-3,3-dimethyl-6-oxocyclohex-1-enyl-1-((Z)-N,N-benzyl-2'-<4',5'-dimethyl-1'-phenyl>hexa-3',5'-dienyl)carboxamide 

Relevant academic research and scientific papers

Bis-Michael Acceptors as Novel Probes to Study the Keap1/Nrf2/ARE Pathway

Nuclear factor erythroid 2-related factor 2 (Nrf2) is a master regulator that promotes the transcription of cytoprotective genes in response to oxidative/electrophilic stress. Various Michael-type compounds were designed and synthesized, and their potency