82495-84-9Relevant articles and documents
Bis-Michael Acceptors as Novel Probes to Study the Keap1/Nrf2/ARE Pathway
Deny, Ludovic J.,Traboulsi, Hussein,Cantin, André M.,Marsault, éric,Richter, Martin V.,Bélanger, Guillaume
, p. 9431 - 9442 (2016/11/11)
Nuclear factor erythroid 2-related factor 2 (Nrf2) is a master regulator that promotes the transcription of cytoprotective genes in response to oxidative/electrophilic stress. Various Michael-type compounds were designed and synthesized, and their potency