82508-07-4

Basic information

• Product Name: Propanoic acid, 2-[[(4-nitrophenyl)sulfonyl]oxy]-, methyl ester, (S)-
• CAS NO: 82508-07-4
• Molecular Formula: C10H11NO7S
• Molecular Weight: 289.266
• Mol File: 82508-07-4.mol
• Article Data: 4

Chemical Properties

• CAS DataBase Reference: Propanoic acid, 2-[[(4-nitrophenyl)sulfonyl]oxy]-, methyl ester, (S)-(CAS DataBase Reference)
• NIST Chemistry Reference: Propanoic acid, 2-[[(4-nitrophenyl)sulfonyl]oxy]-, methyl ester, (S)-(82508-07-4)
• EPA Substance Registry System: Propanoic acid, 2-[[(4-nitrophenyl)sulfonyl]oxy]-, methyl ester, (S)-(82508-07-4)

Safety Data

• Hazardous Substances Data: 82508-07-4(Hazardous Substances Data)

Upstream product

• 27871-49-4 (S)-Methyl lactate 
• 98-74-8 4-Nitrobenzenesulfonyl chloride 

Downstream Products

• 57646-33-0 methyl (2R)-2-[(2,6-dimethylphenyl)amino]propanoate 
• 130608-07-0 tert-butyl 2-((R)-2-methoxy-1-methyl-2-oxoethyl)hydrazinecarboxylate 
• 130518-03-5 tert-butyl 2-((S)-2-methoxy-1-methyl-2-oxoethyl)hydrazinecarboxylate 
• 75386-37-7 (R)-(+)-N-(2-Ethyl-6-methyl-phenyl)-alaninmethylester 

Relevant articles and documents

The influence of atropisomerism and chiral centre on the biological activity of metolachlor

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Preparation of (R)-2-azidoesters from 2-((p-nitrobenzene)sulfonyl)oxy esters and their use as protected amino acid equivalents for the synthesis of di- and tripeptides containing D-amino acid constituents

(R)-2-Azidoesters and their derived (R)-2-azido acids are readily prepared from common amino acids by an inversion methodology that employs (S)-2-nosyloxyesters as key intermediates. The (R)-2-azidoesters can be used as protected amino acid equivalents in peptide synthesis. Basic hydrolysis frees the carboxyl group. Triphenylphosphine/water is used to free the amine group. By these reactions a variety of L-D and D-L dipeptides, L-D-L tripeptides, and depsipeptides can be prepared easily in good yields, and without detectable epimerization.