825600-93-9Relevant academic research and scientific papers
Mechanism of the carbopalladation of alkynes by aryl-palladium complexes
Amatore, Christian,Bensalem, Samia,Ghalem, Said,Jutand, Anny
, p. 4642 - 4646 (2007/10/03)
The carbopalladation between PhPdI(PPh3)2 and EtO2C-CCH gives EtO2C-C(PdIL2)CHPh 1, the trans-adduct as the major complex formed by isomerization of the primary cis-adduct EtO2C-C(PdIL2)CHPh 2. A multicarbopalladation is also observed. The reaction between trans-PhPdI(PPh3)2 and EtO2C-CCH has been investigated. This carbopalladation step involved in palladium-catalyzed multicomponent reactions with alkynes gives the unusual trans-adduct EtO2C-C(PdIL2)CHPh 1 as the major complex formed by isomerization of the primary cis-adduct EtO 2C-C(PdIL2)CHPh 2. The carbopalladation was regiospecific. A multicarbopalladation was also observed by successive carbopalladation of EtO2C-CCH by the vinyl-palladium complexes themselves generated in carbopalladation steps, leading to cationic complexes.
