825611-51-6

Basic information

• Product Name: Phenol, 2-[1-phenyl-3-(1,2,3,4-tetrahydro-3-phenyl-2-naphthalenyl)-1H-pyrazol-5 -yl]-
• CAS NO: 825611-51-6
• Molecular Formula: C31H26N2O
• Molecular Weight: 442.56
• Mol File: 825611-51-6.mol

Chemical Properties

• CAS DataBase Reference: Phenol, 2-[1-phenyl-3-(1,2,3,4-tetrahydro-3-phenyl-2-naphthalenyl)-1H-pyrazol-5 -yl]-(CAS DataBase Reference)
• NIST Chemistry Reference: Phenol, 2-[1-phenyl-3-(1,2,3,4-tetrahydro-3-phenyl-2-naphthalenyl)-1H-pyrazol-5 -yl]-(825611-51-6)
• EPA Substance Registry System: Phenol, 2-[1-phenyl-3-(1,2,3,4-tetrahydro-3-phenyl-2-naphthalenyl)-1H-pyrazol-5 -yl]-(825611-51-6)

Safety Data

• Hazardous Substances Data: 825611-51-6(Hazardous Substances Data)

Upstream product

• 2471-91-2 1,3-dihydrobenzo[c]thiophene-2,2-dioxide 
• 825611-42-5 5-(2-hydroxyphenyl)-1-phenyl-3-styrylpyrazole 
• 931-55-5 phenyl-diazene 
• 126525-72-2 1-(2-hydroxyphenyl)-5-phenyl-4-pentene-1,3-dione 

Relevant articles and documents

3(5)-(2-Hydroxyphenyl)-5(3)-styrylpyrazoles: Synthesis and diels - Alder transformations

Reactions between cinnamoyl(2-hydroxybenzoyl)methanes and hydrazine hydrate in acetic acid gave 3-(2-hydroxyphenyl)-5-styrylpyrazoles, while the corresponding reactions with phenylhydrazine yielded 5-(2-hydroxyphenyl)-l- phenyl-3-styrylpyrazoles as the major products and 3-(2-hydroxyphenyl)-1-phenyl- 5-styrylpyrazoles as by-products. The reaction mechanism of this transformation is discussed. The first cycloaddition reactions between ortho- benzoquinodimethane and either 3-(2-hydroxyphenyl)-5-styrylpyrazoles or 5-(2-hydroxyphenyl)-1-phenyl-3-styrylpyrazoles afforded 5-[2-(3 aryl-1,2,3,4-tetrahydronaphthyl)]-3-(2-hydroxyphenyl)-pyrazoles or 3-[2-(3-aryl-1,2,3,4-tetrahydronaphthyl)]-1-phenyl-5-(2-hydroxyphenyl)pyrazoles, respectively. These cycloadducts were converted into the corresponding naphthylpyrazoles by oxidation with DDQ in dry 1,4-dioxane. The structures of all new derivatives have been established by NMR spectroscopy. Wiley-VCH Verlag GmbH & Co. KGaA, 69451 Weinheim, Germany, 2004.