825633-62-3

Upstream product

• 1826-67-1 vinyl magnesium bromide 
• 851724-09-9 [(1R,2S)-2-Benzyloxy-1-(4-methoxy-phenoxymethyl)-3-oxo-propyl]-carbamic acid tert-butyl ester 
• 825633-61-2 (2S,3R)-2-Benzyloxy-3-tert-butoxycarbonylamino-4-(4-methoxy-phenoxy)-butyric acid ethyl ester 
• 544455-39-2 (2S,3R)-3-Acetylamino-2-hydroxy-4-(4-methoxy-phenoxy)-butyric acid ethyl ester 
• 544455-38-1 ethyl (2E)-4-(4-methoxyphenoxy)but-2-enoate 

Downstream Products

• 873014-41-6 Toluene-4-sulfonic acid (E)-(5S,6S,7R)-6-benzyloxy-7-tert-butoxycarbonylamino-5-hydroxy-8-(4-methoxy-phenoxy)-oct-3-enyl ester 
• 873014-44-9 (1S,2S,3R,7S,7aS)-2-Benzyloxy-3-(4-methoxy-phenoxymethyl)-hexahydro-pyrrolizine-1,7-diol 
• 873014-45-0 (1S,2S,3R,7R,7aR)-2-Benzyloxy-3-(4-methoxy-phenoxymethyl)-hexahydro-pyrrolizine-1,7-diol 

Relevant academic research and scientific papers

A general asymmetric route for the synthesis of the alexine and australine family of pyrrolizidine alkaloids. The first asymmetric synthesis of 1,2-diepi-alexine and 1,2,7-triepi-australine

The first asymmetric synthesis of 1,2-diepi-alexine and 1,2,7-triepi-australine (both are unknown at present) is described, which utilized the regioselective asymmetric aminohydroxylation (RAA) reaction of the achiral olefin VI, the cross metathesis (CM)