82575-12-0

Upstream product

• 103-82-2 phenylacetic acid 
• 4637-24-5 N,N-dimethyl-formamide dimethyl acetal 
• 75245-36-2 α-(1-Hydroxy-2-propenyl)benzenessigsaeure 

Downstream Products

• 126109-87-3 methyl 2-phenyl-3-(trimethylsiloxy)-4-pentenoate 
• 126109-89-5 methyl 3-(tert-butyldimethylsiloxy)-2-phenyl-4-pentenoate 
• 53847-14-6 4-phenyl-1,5-hexadien-3-ol 
• 126109-94-2 3-phenylbicyclo<2.1.1>hexan-2-on 
• 126109-92-0 3-(tert-butyldimethylsiloxy)-4-phenyl-1,5-hexadiene 
• 126109-91-9 3-(tert-butyldimethylsiloxy)-2-phenyl-4-pentenal 
• 126109-93-1 4-phenyl-1,5-hexadien-3-ol pyruvate ester 
• 126109-90-8 3-(tert-butyldimethylsiloxy)-2-phenyl-4-penten-1-ol 

Relevant academic research and scientific papers

The Influence of Intramolecular Dynamics on Branching Ratios in Thermal Rearrangements

1- and 2-phenylbicyclohex-2-enes-5-d undergo thermal rearrangement to give products, differing only in the location of the deuterium, in ratio of about 9:1, but with identical activation enthalphies.Similarly, opticallly active trans-2-methyl-1-(trans-2-phenylethenyl)cyclopropane is found to rearrange to enantiomeric methylphenylcyclopentenes that are formed in a 5.9:1 ratio but with virtually identicyl activation enthalphies.Barring repeated coincidence, these results do not seem to be explicable within the framework of statistical theories of unimolecular kinetics such as RRKM theory, transition state theory, and variational transition state theory.The possible influence of dynamic effects in these and other unimolecular reactions is discussed.

Dehydrative Decarboxylation of 2,3-Disubstituted 3-Hydroxycarboxylic Acids with Dimethylformamide Acetals - Mechanistic Studies and Preparative Applicability

Dimethylformamide dimethylacetal (2a) converts the threo-3-hydroxycarboxylic acids 4 smoothly into the (E)/(Z)-olefins 7/6 only if R2 is an aryl or vinyl substituent.Althougt the reaction exhibits a distinct (E)-selectivity it cannot be considered as a stereo-controlled olefin synthesis.If R2 is alkyl, 2a generates the methyl esters 10 from 4.The erythro-acids 5 react with 2a to give 43 - 95percent of >98percent sterically pure 7.As the key tranformation on the multistep way from 4/5 to 6/7 the fragmentation of the zwitterionic intermediate 11/20 is postulated.