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N,N-bis(2-chloroethyl)-3-(2,2,6,6-tetramethylpiperidin-4-yl)-1,3,2-oxazaphosphinan-2-amine 2-oxide is a chemical compound that belongs to the class of organic compounds known as alkyl phosphorochloridothioates. It is a powerful bifunctional alkylating agent, commonly used in chemotherapy and cancer treatment. N,N-bis(2-chloroethyl)-3-(2,2,6,6-tetramethylpiperidin-4-yl)-1,3,2-oxazaphosphinan-2-amine 2-oxide is known for its ability to crosslink DNA, causing damage to the genetic material of cancer cells and ultimately leading to cell death.

82576-63-4

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82576-63-4 Usage

Uses

Used in Cancer Treatment:
N,N-bis(2-chloroethyl)-3-(2,2,6,6-tetramethylpiperidin-4-yl)-1,3,2-oxazaphosphinan-2-amine 2-oxide is used as a chemotherapeutic agent for the treatment of various types of cancer. Its ability to crosslink DNA makes it effective in damaging the genetic material of cancer cells, leading to cell death and potentially reducing tumor growth.
Used in Pharmaceutical Industry:
In the pharmaceutical industry, N,N-bis(2-chloroethyl)-3-(2,2,6,6-tetramethylpiperidin-4-yl)-1,3,2-oxazaphosphinan-2-amine 2-oxide is used as an active pharmaceutical ingredient in the development of cancer drugs. Its potent alkylating properties make it a valuable component in the creation of medications designed to combat cancer.
However, due to its high risk of toxicity and adverse side effects, N,N-bis(2-chloroethyl)-3-(2,2,6,6-tetramethylpiperidin-4-yl)-1,3,2-oxazaphosphinan-2-amine 2-oxide is a highly regulated and controlled substance. It is crucial to handle and administer N,N-bis(2-chloroethyl)-3-(2,2,6,6-tetramethylpiperidin-4-yl)-1,3,2-oxazaphosphinan-2-amine 2-oxide with extreme caution and under strict medical supervision to minimize potential harm to patients.

Check Digit Verification of cas no

The CAS Registry Mumber 82576-63-4 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 8,2,5,7 and 6 respectively; the second part has 2 digits, 6 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 82576-63:
(7*8)+(6*2)+(5*5)+(4*7)+(3*6)+(2*6)+(1*3)=154
154 % 10 = 4
So 82576-63-4 is a valid CAS Registry Number.

82576-63-4SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 11, 2017

Revision Date: Aug 11, 2017

1.Identification

1.1 GHS Product identifier

Product name N,N-bis(2-chloroethyl)-2-oxo-3-(2,2,6,6-tetramethylpiperidin-4-yl)-1,3,2λ<sup>5</sup>-oxazaphosphinan-2-amine

1.2 Other means of identification

Product number -
Other names N,N-bis(2-chloroethyl)-3-(2,2,6,6-tetramethyl-4-piperidinyl)tetrahydro-2H-1,3,2-oxazaphosphorin-2-amine 2-oxide

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:82576-63-4 SDS

82576-63-4Downstream Products

82576-63-4Relevant academic research and scientific papers

Synthesis and study of a spin-labeled cyclophosphamide analogue, 3-(1-oxy-2,2,6,6-tetramethyl-4-piperidinyl)cyclophosphamide

Tsui,Robey,Engle,Ludeman,Zon

, p. 1106 - 1110 (1982)

3-(1-Oxy-2,2,6,6-tetramethyl-4-piperidinyl)cyclophosphamide (7) was isolated in 36% yield following H2O2-Na2WO4 oxidation of 3-(2,2,6,6-tetramethyl-4-piperidinyl)cyclophosphamide (6), which was synthesized in th

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