82578-51-6

Basic information

• Product Name: 2-(2-hydroxyethoxy)ethyl 2-{[4-hydroxy-3-(trifluoromethyl)phenyl]amino}benzoate
• Synonyms: 2-(2-Hydroxyethoxy)ethyl N-(4-hydroxy-3-trifluoromethylphenyl)anthranilat
• CAS NO: 82578-51-6
• Molecular Formula: C₁₈H₁₈F₃NO₅
• Molecular Weight: 385.3344
• Mol File: 82578-51-6.mol
• Article Data: 1

Chemical Properties

• Boiling Point: 465.5°C at 760 mmHg
• Flash Point: 235.3°C
• Density: 1.382g/cm³
• Vapor Pressure: 1.82E-09mmHg at 25°C
• Refractive Index: 1.57
• CAS DataBase Reference: 2-(2-hydroxyethoxy)ethyl 2-{[4-hydroxy-3-(trifluoromethyl)phenyl]amino}benzoate(CAS DataBase Reference)
• NIST Chemistry Reference: 2-(2-hydroxyethoxy)ethyl 2-{[4-hydroxy-3-(trifluoromethyl)phenyl]amino}benzoate(82578-51-6)
• EPA Substance Registry System: 2-(2-hydroxyethoxy)ethyl 2-{[4-hydroxy-3-(trifluoromethyl)phenyl]amino}benzoate(82578-51-6)

Safety Data

• Hazardous Substances Data: 82578-51-6(Hazardous Substances Data)

Upstream product

• 82578-52-7 4'-Benzyloxy-flufenaminsaeuremethylester 
• 82584-60-9 2-(4-Benzyloxy-3-trifluoromethyl-phenylamino)-benzoic acid 2-(2-hydroxy-ethoxy)-ethyl ester 

Relevant articles and documents

Synthesis and properties of nuclear hydroxylated derivatives of flufenamic acid and etofenamate

Synthesis of six nuclear hydroxylated derivatives of flufenamic acid and etofenamate (5-OH-, 4'-OH and 5,4'-(OH2) on a preparative scale is described. All compounds show low toxicity, by only weak anti-inflammatory activity in the rat paw kaolin edema test as compared to 2-(2-hydroxyethoxy)ethyl-N-(α,α,α-trifluoro-m-tolyl)-anthranilate (etofenamate, active substance of Rheumon Gel).