82588-42-9

Basic information

• Product Name: 6-(4-METHYLPHENYL)IMIDAZO[2,1-B][1,3]THIAZOLE-5-CARBALDEHYDE
• Synonyms: 6-P-TOLYL-IMIDAZO[2,1-B]THIAZOLE-5-CARBALDEHYDE;6-(4-METHYLPHENYL)IMIDAZO[2,1-B][1,3]THIAZOLE-5-CARBALDEHYDE
• CAS NO: 82588-42-9
• Molecular Formula: C₁₃H₁₀N₂OS
• Molecular Weight: 242.3
• Mol File: 82588-42-9.mol
• Article Data: 4

Chemical Properties

• Melting Point: 167-169°C
• Appearance: /
• Density: 1.32g/cm³
• Refractive Index: 1.695
• CAS DataBase Reference: 6-(4-METHYLPHENYL)IMIDAZO[2,1-B][1,3]THIAZOLE-5-CARBALDEHYDE(CAS DataBase Reference)
• NIST Chemistry Reference: 6-(4-METHYLPHENYL)IMIDAZO[2,1-B][1,3]THIAZOLE-5-CARBALDEHYDE(82588-42-9)
• EPA Substance Registry System: 6-(4-METHYLPHENYL)IMIDAZO[2,1-B][1,3]THIAZOLE-5-CARBALDEHYDE(82588-42-9)

Safety Data

• HazardClass: IRRITANT
• Hazardous Substances Data: 82588-42-9(Hazardous Substances Data)

Usage

General Description

6-(4-methylphenyl)imidazo[2,1-b][1,3]thiazole-5-carbaldehyde is a chemical compound with the molecular formula C13H10N2OS. It is a heterocyclic organic compound containing an imidazole and thiazole ring system, as well as a benzene ring with a methyl group. 6-(4-METHYLPHENYL)IMIDAZO[2,1-B][1,3]THIAZOLE-5-CARBALDEHYDE is a carbaldehyde, meaning it contains an aldehyde functional group. It is used in organic synthesis and medicinal chemistry as a building block for the creation of other compounds. The specific properties and uses of this compound may vary depending on the context in which it is being utilized.

InChI:InChI=1/C13H10N2OS/c1-9-2-4-10(5-3-9)12-11(8-16)15-6-7-17-13(15)14-12/h2-8H,1H3

Upstream product

• 7008-64-2 6-(4-tolyl)imidazo<2,1-b>thiazole 
• 68-12-2 N,N-dimethyl-formamide 
• 619-41-0 4-(bromoacetyl)toluene 

Downstream Products

• 82588-60-1 5-Hydroxymethyl-6-p-tolylimidazo<2,1-b>thiazole 
• 102410-34-4 Dimethylamino-acetic acid [1-(6-p-tolyl-imidazo[2,1-b]thiazol-5-yl)-meth-(E)-ylidene]-hydrazide 

Relevant articles and documents

DL5050, a Selective Agonist for the Human Constitutive Androstane Receptor

The constitutive androstane receptor (CAR) is a xenobiotic sensor governing the transcription of genes involved in drug disposition, energy homeostasis, and cell proliferation. However, currently available human CAR (hCAR) agonists are nonselective, which

CAR ACTIVATOR AGENTS FOR CYCLOPHOSPHAMIDE-BASED TREATMENTS OF CANCER

The invention relates to selective small molecule human constitutive androstane receptor (hCAR) activators of Formula (I) or (II), pharmaceutical compositions thereof, and use thereof for the treatment of hematologic malignancies and other cancers. The sm