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2,3-dimethoxy-7,7a,8,9,10,12-hexahydrobenzo[h]pyrrolo[1,2-b]isoquinoline is a chemical with a specific purpose. Lookchem provides you with multiple data and supplier information of this chemical.

82589-60-4

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82589-60-4 Usage

Specific content

Chemical compound name

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Popular name for the compound

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Medicine systems that have used Nantenine

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Possible effects of the compound on mental health

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Investigated areas of Nantenine's potential benefits

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Conditions for which Nantenine has been considered as a natural remedy

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Current state of scientific understanding and investigation of Nantenine

Occurrence

Found in several plants, including Nandina domestica and Nelumbo nucifera

Traditional use

Chinese and Ayurvedic medicine

Potential properties

Antidepressant, anxiolytic, and sedative

Research areas

Neuroprotective and anti-inflammatory effects

Potential applications

Anxiety, depression, and neurodegenerative diseases

Research status

More research needed to understand mechanisms of action and medicinal uses

Check Digit Verification of cas no

The CAS Registry Mumber 82589-60-4 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 8,2,5,8 and 9 respectively; the second part has 2 digits, 6 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 82589-60:
(7*8)+(6*2)+(5*5)+(4*8)+(3*9)+(2*6)+(1*0)=164
164 % 10 = 4
So 82589-60-4 is a valid CAS Registry Number.

82589-60-4Downstream Products

82589-60-4Relevant academic research and scientific papers

Synthesis of Hexahydropyrroloisoquinolines - Analogs of Phenanthroindolizidine Anticancer Alkaloids

Gaur, S. P.,Jain, Padam C.,Anand, Nitya

, p. 46 - 51 (2007/10/02)

A convenient preparative route has been developed for the synthesis of hexahydropyrroloisoquinolines involving condensation of an araldehyde with ethyl 4-nitrobutanoate followed by LAH reduction and subsequent cyclization with H2SO4 to 2-arylmethylpyrrolidines.The latter on formylation and Bischler-Napieralsky cyclization followed by NaBH4 reduction give the required pyrroloisoquinolines.Using this method, 8-methoxy-1,2,3,5,10,10a-hexahydropyrroloisoquinoline (IXa); 7,8-dimethoxy-1,2,3,5,10,10a-hexahydropyrroloisoquinoline (IXb); 7,9,10,11,11a,12-hexahydrobenzopyrroloisoquinoline (Xa); 3-methoxy-7,9,10,11,11a,12-hexahydrobenzopyrroloisoquinoline (Xb); 7,7a,8,9,10,12-hexahydrobenzopyrroloisoquinoline (XIa); 3-methoxy-7,7a,8,9,10,12-hexahydrobenzopyrroloisoquinoline (XIb) and 2,3-dimethoxy-7,7a,8,9,10,12-hexahydrobenzopyrroloisoquinoline (XIc) have been synthesized.None of these compounds has shown any noteworthy anticancer activity while few have exhibited interesting antihistaminic, β-blocking, hypertensive, antiinflammatory and antireserpine activities.

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