82601-41-0 Usage
General Description
Pseudolaric Acid C is a natural chemical compound isolated from the bark of the tree Pseudolarix kaempferi. It is a diterpene acid with potent biological activities, including anti-inflammatory, anti-tumor, and anti-fungal properties. Pseudolaric Acid C has been found to inhibit the growth of various cancer cells and induce apoptosis, making it a potential candidate for cancer therapy. In addition, it has shown promise in the treatment of inflammatory and fungal diseases. The compound's unique structure and biological activities make it a subject of interest for further research and potential development of pharmaceutical applications.
Check Digit Verification of cas no
The CAS Registry Mumber 82601-41-0 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 8,2,6,0 and 1 respectively; the second part has 2 digits, 4 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 82601-41:
(7*8)+(6*2)+(5*6)+(4*0)+(3*1)+(2*4)+(1*1)=110
110 % 10 = 0
So 82601-41-0 is a valid CAS Registry Number.
InChI:InChI=1/C21H26O7/c1-13(16(22)23)5-4-9-19(2)15-8-11-20(18(25)28-19)10-6-14(17(24)27-3)7-12-21(15,20)26/h4-6,9,15,26H,7-8,10-12H2,1-3H3,(H,22,23)/b9-4+,13-5+/t15-,19+,20+,21-/m0/s1
82601-41-0Relevant articles and documents
Synthesis and biological evaluation of pseudolaric acid B derivatives as potential immunosuppressive agents
Chen, Shou-Qiang,Wang, Jie,Zhao, Chuan,Sun, Qiang-Wen,Wang, Yi-Teng,Ai, Ting,Li, Tan,Gao, Ying,Wang, Huo,Chen, Hong
, p. 828 - 837 (2015)
Pseudolaric acid B (PB) derivatives with immunosuppressive activity were found by our group. In order to find potential immunosuppressive agents with high efficacy and low toxicity, a series of novel PB derivatives were synthesized and evaluated on their immunosuppressive activities. Most of the synthesized compounds were tested in vitro on murine T and B proliferation. In particular, compound 11 exhibited excellent inhibitory activity toward murine T cells (up to 19-fold enhancement compared to that of mycophenolatemofetil) and little cytotoxicity toward normal murine spleen cells. These experimental data demonstrated that some of these PB derivatives have great potential for future immunosuppressive studies.
