82619-71-4Relevant academic research and scientific papers
Solution-phase parallel synthesis of 4,6-diaryl-pyrimidine-2-ylamines and 2-amino-5,5-disubstituted-3,5-dihydro-imidazol-4-ones via a rearrangement
Varga, László,Nagy, Tamás,K?vesdi, István,Benet-Buchholz, Jordi,Dormán, Gy?rgy,ürge, László,Darvas, Ferenc
, p. 655 - 662 (2007/10/03)
The reaction of chalcones and guanidine was investigated in the presence of an oxidizing agent. Depending on the order of the addition either a 4,6-diaryl-pyrimidine-2-ylamine or 2-amino-5,5-disubstituted-3,5-dihydro-imidazol-4-one was obtained. The structures of the imidazolinones were elucidated by NMR spectroscopy and X-ray crystallography and for its formation a mechanism was proposed.
