82635-56-1

Basic information

• Product Name: 7,8-dimethoxy-5H-pyrrolo[2,1-c][1,4]benzodiazepine-5,11(10H)-dione
• CAS NO: 82635-56-1
• Molecular Formula: C₁₄H₁₂N₂O₄
• Molecular Weight: 272.2561
• Mol File: 82635-56-1.mol
• Article Data: 1

Chemical Properties

• Boiling Point: 332.1°C at 760 mmHg
• Flash Point: 154.7°C
• Density: 1.4g/cm³
• Vapor Pressure: 0.000149mmHg at 25°C
• Refractive Index: 1.648
• CAS DataBase Reference: 7,8-dimethoxy-5H-pyrrolo[2,1-c][1,4]benzodiazepine-5,11(10H)-dione(CAS DataBase Reference)
• NIST Chemistry Reference: 7,8-dimethoxy-5H-pyrrolo[2,1-c][1,4]benzodiazepine-5,11(10H)-dione(82635-56-1)
• EPA Substance Registry System: 7,8-dimethoxy-5H-pyrrolo[2,1-c][1,4]benzodiazepine-5,11(10H)-dione(82635-56-1)

Safety Data

• Hazardous Substances Data: 82635-56-1(Hazardous Substances Data)

Upstream product

• 29568-78-3 4,5-dimethoxy-2-nitrobenzoyl chloride 
• 1193-62-0 methyl Pyrrole-2-carboxylate 
• 82635-52-7 1-(4,5-Dimethoxy-2-nitro-benzoyl)-1H-pyrrole-2-carboxylic acid methyl ester 

Relevant articles and documents

Potential Anticancer Agents: Synthesis of Some Substituted Pyrrolobenzodiazepines

A number of substituted pyrrolobenzodiazepines have been synthesised starting from appropriately substituted 2-nitrobenzoyl chloride by condensation with methyl pyrrole-2-carboxylate, followed by reduction and cyclisation.These compounds have been screened for their anticancer activity against lymphoid L-1210 but none shows any noteworthy activity.