82650-07-5

Basic information

• Product Name: L-Threonine hydrochloride
• Synonyms: L-THREONINE HYDROCHLORIDE SOLUTION;L-Threonine hydrochloride;L-Threonine solution hydrochloride;(2S,3R)-2-aMino-3-hydroxybutanoic acid hydrochloride
• CAS NO: 82650-07-5
• Molecular Formula: C₄H₉NO₃*ClH
• Molecular Weight: 155.58
• EINECS: 231-791-2
• Product Categories: Amino Acids, Peptides and Proteins;Amino AcidsAlphabetic;Life Sciences Standards;TF - TO
• Mol File: 82650-07-5.mol
• Article Data: 3

Chemical Properties

• Appearance: /
• Storage Temp.: −20°C
• BRN: 5761047
• CAS DataBase Reference: L-Threonine hydrochloride(CAS DataBase Reference)
• NIST Chemistry Reference: L-Threonine hydrochloride(82650-07-5)
• EPA Substance Registry System: L-Threonine hydrochloride(82650-07-5)

Safety Data

• RIDADR: UN 1789 8/PG 3
• WGK Germany: 2
• F: 10
• Hazardous Substances Data: 82650-07-5(Hazardous Substances Data)

Usage

General Description

L-Threonine hydrochloride is a naturally occurring amino acid that is essential for protein synthesis and various metabolic functions in the body. It is commonly used as a nutritional supplement to improve animal feed and promote healthy growth in livestock. L-Threonine also plays a crucial role in supporting the immune system and maintaining proper muscle function. As a hydrochloride salt form, it is more stable and easier to handle than the free form, making it a preferred choice for use in various pharmaceutical and industrial applications. Additionally, it can be utilized in the production of pharmaceuticals, chemicals, and food additives, as well as in the development of cosmetics and personal care products.

InChI:InChI=1/C4H9NO3.ClH/c1-2(6)3(5)4(7)8;/h2-3,6H,5H2,1H3,(H,7,8);1H/t2?,3-;/m0./s1

Upstream product

• 1207348-80-8 micropeptin MZ₇₇₁ 
• 1383580-56-0 (2S,4S)-N-((6R,9R,12S,15S,16R,Z)-3-ethylidene-6-(4-hydroxybenzyl)-12-isobutyl-9-isopropyl-16-methyl-2,5,8,11,14-pentaoxo-1-oxa-4,7,10,13-tetraazacyclohexadecan-15-yl)-2,4-dimethylheptanamide 
• 1447695-69-3 cycloforskamide 
• 1207348-78-4 micropeptin MZ₁₀₁₉ 
• 1207348-76-2 micropeptin MZ₉₃₉B 
• 1207348-74-0 micropeptin MZ₉₂₅ 
• 1207348-72-8 micropeptin MZ₉₃₉A 
• 1207348-70-6 micropeptin MZ₈₅₉ 
• 914606-75-0 micropeptin MZ₈₄₅ 

Downstream Products

• 39994-75-7 (+/-) threonine methyl ester hydrochloride 
• 39994-75-7 H-DL-aThr-OMe*HCl 
• 72-19-5 L-threonine 
• 60538-17-2 (4S,5R)-4-methyl-2-phenyl-4,5-dihydrooxazole-4-carboxylic acid methyl ester 
• 33209-01-7 L-threonine amide hydrochloride 
• 80110-55-0 Boc-Tyr-Thr-OH 

Relevant articles and documents

Cycloforskamide, a cytotoxic macrocyclic peptide from the sea slug Pleurobranchus forskalii

A macrocylic dodecapeptide, cycloforskamide, was isolated from the sea slug Pleurobranchus forskalii, collected off Ishigaki Island, Japan. Its planar structure was deduced by extensive NMR analyses and was further confirmed by MS/MS fragmentation analyses. Finally, the absolute configuration was determined by total hydrolysis and chiral-phase gas chromatographic analysis. This novel dodecapeptide contains three d-amino acids and three thiazoline heterocycles and exhibits cytotoxicity against murine leukemia P388 cells, with an IC 50 of 5.8 μM.

Micropeptins from an Israeli fishpond water bloom of the cyanobacterium microcystis sp

Seven new natural products, micropeptin MZ845 (1), micropeptin MZ859 (2), micropeptin MZ939A (3), micropeptin MZ925 (4), micropeptin MZ939B (5), micropeptin MZ1019 (6), and micropeptin MZ771 (7), as well as two known micropeptins, cyanopeptolin S (8) and cyanopeptolin SS (9), were isolated from the hydrophilic extract of the cyanobacterium Microcystis sp. that was collected from a fishpond in Kibbutz Ma'ayan Tzvi, Israel, in July 2006. The structures of the pure natural products were elucidated using spectroscopic methods, including UV, 1D and 2D NMR, and MS techniques. The absolute configuration of the chiral centers of the compounds was determined using Marfey's method for HPLC. The inhibitory activity of the compounds was determined for the serine proteases: trypsin, chymotrypsin, thrombin, and elastase. These micropeptins inhibited trypsin with IC50's that varied between 0.6 and 24.2 μM. The SAR of these micropeptins is discussed.