82657-72-5

Basic information

• Product Name: 1-(BROMOMETHYL)-2-PHENOXYBENZENE
• Synonyms: 2-PHENOXYBENZYL BROMIDE;1-(BROMOMETHYL)-2-PHENOXYBENZENE;2-Phenoxybenzyl bromide 90%;1-(bromothyl)-2-phenoxybenzene;2-Phenoxybenzylbromide90%
• CAS NO: 82657-72-5
• Molecular Formula: C₁₃H₁₁BrO
• Molecular Weight: 263.13
• Mol File: 82657-72-5.mol
• Article Data: 9

Chemical Properties

• Boiling Point: 317.158°C at 760 mmHg
• Flash Point: 125.004°C
• Appearance: /
• Density: 1.388g/cm³
• Vapor Pressure: 0.001mmHg at 25°C
• Refractive Index: 1.606
• CAS DataBase Reference: 1-(BROMOMETHYL)-2-PHENOXYBENZENE(CAS DataBase Reference)
• NIST Chemistry Reference: 1-(BROMOMETHYL)-2-PHENOXYBENZENE(82657-72-5)
• EPA Substance Registry System: 1-(BROMOMETHYL)-2-PHENOXYBENZENE(82657-72-5)

Safety Data

• Hazard Codes: Xi
• HazardClass: 8
• Hazardous Substances Data: 82657-72-5(Hazardous Substances Data)

Usage

Uses

1-(Bromomethyl)-2-phenoxybenzene is used in the preparation of CRAC channels using photoswitchable azopyrazoles.

InChI:InChI=1/C13H11BrO/c14-10-11-6-4-5-9-13(11)15-12-7-2-1-3-8-12/h1-9H,10H2

Upstream product

• 19434-34-5 2-(phenoxy)benzaldehyde 
• 2243-42-7 2-phenoxybenzoic acid 
• 21905-56-6 methyl 2-phenoxybenzoate 
• 13807-84-6 (2-phenoxyphenyl)methanol 
• 3991-61-5 1-methyl-2-phenoxybenzene 

Downstream Products

• 107624-14-6 (2-phenoxyphenyl)methanamine 
• 19434-34-5 2-(phenoxy)benzaldehyde 
• 948850-53-1 2-phenoxybenzylzinc bromide 
• 361212-34-2 5-((2-phenoxybenzyloxy)methyl)-3-triphenylmethyl-4,5,6,7-tetrahydro-3H-benzimidazole 
• 3991-61-5 1-methyl-2-phenoxybenzene 
• 28994-41-4 o-Benzylphenol 
• 329980-56-5 Br^(1-)*C₃₁H₂₆OP⁽¹⁺⁾ 
• 1384129-37-6 C₂₁H₂₃NO₅ 
• 1373394-69-4 2,6-difluoro-N-(1-{[2-(phenyloxy)phenyl]methyl}-1H-pyrazol-4-yl)benzamide 
• 1181079-95-7 3-(2-chloro-6-trifluoromethylpyridin-3-yl)-5,5-dimethyl-1-(2-phenoxybenzyl)imidazolidine-2,4-dione 
• 1181078-92-1 4-[4,4-Dimethyl-2,5-dioxo-3-(2-phenoxybenzyl)-imidazolidin-1-yl]-benzonitrile 
• 1179906-97-8 tert-butyl 2-methyl-2-(2-phenoxybenzylamino)propionate 
• 1253188-41-8 2-(1-{[2-(phenyloxy)phenyl]methyl}-1H-pyrazol-3-yl)-1H-isoindole-1,3(2H)-dione 
• 1253113-40-4 ethyl 1-{[2-(phenyloxy)phenyl]methyl}-1H-pyrazole-3-carboxylate 

Relevant articles and documents

Optical Control of CRAC Channels Using Photoswitchable Azopyrazoles

The Ca2+ release-activated Ca2+ (CRAC) channels control many Ca2+-modulated physiological processes in mammals. Hyperactivating CRAC channels are known to cause several human diseases, including Stormorken syndrome. Here, we show the design of azopyrazole-derived photoswitchable CRAC channel inhibitors (designated piCRACs), which enable optical inhibition of store-operated Ca2+ influx and downstream signaling. Moreover, piCRAC-1 has been applied in vivo to alleviate thrombocytopenia and hemorrhage in a zebrafish model of Stormorken syndrome in a light-dependent manner.

AMINOPEPTIDASE A INHIBITORS AND PHARMACEUTICAL COMPOSITIONS COMPRISING THE SAME

The present invention relates to a novel compound, to a composition comprising the same, to methods for preparing the compound, and the use of this compound in therapy. In particular, the present invention relates to compound that is useful in the treatment and prevention of primary and secondary arterial hypertension, ictus, myocardial ischaemia, cardiac and renal insufficiency, myocardial infarction, peripheral vascular disease, diabetic proteinuria, Syndrome X and glaucoma.

Arylchalcogenoarylalkyl-substituted imidazolidine-2,4-diones, process for preparation thereof, medicaments comprising these compounds and use thereof

The invention relates to compounds of formula (I) wherein the groups R and R′ A, D, E, G, L, p and R1 to R10 have the stated meanings and to their physiologically compatible salts. Said compounds are suitable, for example, as anti-obesity drugs.