82671-75-8Relevant academic research and scientific papers
2-ETHYNYLAZIRIDINES
Shubina, Yu. V.,Tikhomirov, D. A.,Eremeev, A. V.
, p. 147 - 150 (2007/10/02)
Methods for the synthesis of 2-ethynylaziridines by the cycloaddition of carbene to an α-ethynyl imine, cyclization of acetylenic β-amino alcohols in the presence of triphenylphosphine, and by means of the Gabriel reaction were developed.
Synthesis of 2-ethynylaziridines
Shubina,Tikhomirov,Eremeev
, p. 494 - 498 (2007/10/02)
2-Ethynyl-substituted aziridines were obtained by the reaction of acetylenic β-amino and β-azido alcohols with triphenylphosphine and carbon tetrachloride in the presence of triethylamine. The cycloaddition of carbenes and diazomethane to an acetylenic imine was investigated. 2-Ethynylaziridines were obtained in the case of carbonylalkoxycarbenes. The regioselectivity of the cycloaddition of carbenes to an acetylenic imine is demonstrated.
