82681-92-3Relevant academic research and scientific papers
2,3,6,7,8,9-hexahydro-8,8-dimethyl-5-phenyl-1H-1,4-benzodiazepin-6-one
Egg,Knauseder,Mayr,Schopf
, p. 655 - 657 (1995)
Several approaches for the synthesis of the title compound 1 were investigated. Treatment of the ethane-1,2-diamine derivative 2 with phosphoryl chloride afforded 3-chloro-5,5-dimethylcyclohex-2-enone (3) and 1-(5,5-dimethyl-3-oxocyclohex-1-enyl)-4,5-dihydro-2-phenylimidazole (4). The reaction of 2-benzoyldimedone (5) with an equimolar amount of ethane-1,2-diamine led to the 2:1 adduct 6, whereas with an excess of ethane-1,2-diamine, 4,5-dihydro-2-phenylimidazole (7) and dimedone were obtained. The synthesis of the title compound 1 was achieved by reacting 2-benzoyl-3-chloro-5,5-dimethylcyclohex-2-enone (8) with ethane-1,2-diamine.
Synthesis of Phenyl-Substituted Derivatives of Decahydrophenanthridine-1,7-dione and Hexahydro-8-isoquinolone
Ozols, Ya. Ya.,Pyrko, A. N.,Vigante, B. A.,Dubure, R. R.,Dubur, G. Ya.
, p. 530 - 534 (2007/10/02)
2-Bromo-2-aroylcyclohexan-1-ones were prepared by bromination of 2-aroylcyclohexan-1-ones with N-bromosuccinimide and were isomerized into 6-bromo-2-aroylcyclohexan-1-ones in attempted dehydrobromination by heating in organic solvents.The reaction of 2-be
