827017-67-4Relevant academic research and scientific papers
Synthesis and evaluation of 5-substituted derivatives of 4,5-dihydro-3,3-diethyl-2(3H)-furanone as subtype-selective muscarinic leads
Ahungena, Alemayyehu,Gabriel, Jerome L.,Canney, Daniel J.
, p. 481 - 511 (2007/10/03)
A series of 5-substituted 4,5 dihydro-3,3-diethyl-2(3H)-furanones were prepared and evaluated as ligands for cholinergic receptors. 3,3-Diethyl-5-imidazolylmethyl-2(3H)-furanone (12), showed a three-fold selectivity for the M2 receptor subtype
