827039-16-7

Basic information

• Product Name: 5-Thiazolecarboxylic acid, 2-[cyclohexyl[4-[[2-(trifluoromethyl)phenyl]methoxy]benzoyl]amino]-, ethyl ester
• CAS NO: 827039-16-7
• Molecular Formula: C27H27F3N2O4S
• Molecular Weight: 532.584
• Mol File: 827039-16-7.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 5-Thiazolecarboxylic acid, 2-[cyclohexyl[4-[[2-(trifluoromethyl)phenyl]methoxy]benzoyl]amino]-, ethyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: 5-Thiazolecarboxylic acid, 2-[cyclohexyl[4-[[2-(trifluoromethyl)phenyl]methoxy]benzoyl]amino]-, ethyl ester(827039-16-7)
• EPA Substance Registry System: 5-Thiazolecarboxylic acid, 2-[cyclohexyl[4-[[2-(trifluoromethyl)phenyl]methoxy]benzoyl]amino]-, ethyl ester(827039-16-7)

Safety Data

• Hazardous Substances Data: 827039-16-7(Hazardous Substances Data)

Upstream product

• 827039-12-3 2-[(4-benzyloxy-benzoyl)-cyclohexyl-amino]-thiazole-5-carboxylic acid ethyl ester 
• 827038-82-4 2-(4-benzyloxy-benzoylamino)-thiazole-5-carboxylic acid ethyl ester 
• 1486-50-6 4-(benzyloxy)benzoic acid chloride 
• 32955-21-8 2-amino-thiazole-5-carboxylic acid ethyl ester 
• 827038-61-9 2-[cyclohexyl-(4-hydroxy-benzoyl)-amino]-thiazole-5-carboxylic acid ethyl ester 

Relevant articles and documents

Aminothiazole inhibitors of HCV RNA polymerase

Aminothiazole-based inhibitors designed for HCV polymerase display low micromolar potencies in biochemical assays. These compounds show a stringent preference for a cyclohexyl hydrophobe at the 2-amino position. The composition of these compounds suggests that they may be interacting at a recently discovered allosteric site on the polymerase.