82706-21-6Relevant articles and documents
Evaluation of 3-substituted arginine analogs as selective inhibitors of human nitric oxide synthase isozymes
Ijuin, Ryosuke,Umezawa, Naoki,Nagai, Shin-Ichi,Higuchi, Tsunehiko
, p. 2881 - 2885 (2005)
Nitric oxide (NO), a mediator of various physiological and pathophysiological processes, is synthesized by three isozymes of nitric oxide synthase (NOS). In developing candidate clinical drugs, it is very important not to inhibit endothelial NOS, because
BRIDGED TRICYCLIC CARBAMOYLPYRIDONE COMPOUNDS AND THEIR PHARMACEUTICAL USE
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Paragraph 0868, (2020/10/20)
Compounds for use in treating or preventing human immunodeficiency virus (HIV) infection are disclosed. The compounds have the following formula (I): including stereoisomers and pharmaceutically acceptable salts thereof, wherein R1, R2, L, W1, W2, X, Y, and Z are as defined herein. Methods associated with the preparation and use of such compounds, as well as pharmaceutical compositions comprising such compounds, are also disclosed.