82746-41-6Relevant articles and documents
Synthesis and biological evaluation of some new indolizine derivatives as antitumoral agents
Lucescu, Liliana,B?cu, Elena,Belei, Dalila,Dubois, Jo?lle,Ghinet, Alina
, p. 479 - 488 (2016/07/19)
A new series of indolizine derivatives were synthesized and screened for the antiproliferative potential against NCI 60 tumor cell line panel. The results of the study revealed a selective and good antitumor growth inhibitory activity against SNB-75 CNS c
Discovery of indolizines containing triazine moiety as new leads for the development of antitumoral agents targeting mitotic events
Lucescu, Liliana,Ghinet, Alina,Belei, Dalila,Rigo, Beno?t,Dubois, Jo?lle,B?cu, Elena
supporting information, p. 3975 - 3979 (2015/08/24)
Abstract A new family of 3-aroylindolizines bearing a dimethoxytriazine unit in their position 1 was designed, synthesized and evaluated for their ability to inhibit tubulin polymerization and cellular growth in vitro. Compound 39 was the best candidate i
Synthesis, photophysical, and electrochemical properties of 2,5-diaryl-indolizines
Amaral, M?nica F.Z.J.,Deliberto, Laila A.,De Souza, Camila R.,Naal, Rose M.Z.G.,Naal, Zeki,Clososki, Giuliano C.
, p. 3249 - 3258 (2014/05/06)
A variety of novel 2,5-diaryl-indolizines have been prepared through the palladium-catalyzed cross-coupling reactions of organozinc reagents prepared from 2-aryl-indolizines with aromatic halides. The photophysical properties of representative compounds indicate that the 2,5-diaryl-indolizines are promising candidates to be used in optoelectronic devices and biomolecular labeling. In addition, cyclic voltammetry studies of some nitrophenyl-substituted indolizines have shown evidences of an oxidation process without the correspondent reduction peak suggesting a dimerization reaction.