82747-56-6 Usage
Description
Cicletanine Hydrochloride is a furopyridine derivative that functions as an antihypertensive diuretic, specifically indicated for the treatment of essential hypertension. Its mechanism of action is unique, as it decreases peripheral resistance and increases venous compliance without altering arterial diameter or venous tone. Chemically, it does not belong to any currently known pharmacological classes, making it a distinct compound in the field of hypertension management.
Uses
Used in Pharmaceutical Industry:
Cicletanine Hydrochloride is used as an antihypertensive agent for the treatment of essential hypertension. It is effective in reducing blood pressure due to its unique mechanism of action that involves decreasing peripheral resistance and increasing venous compliance without modifying arterial diameter and venous tone.
Used in Pharmaceutical Industry:
Cicletanine Hydrochloride is used as a diuretic agent, exhibiting a natriuretic effect comparable to that of hydrochlorothiazide and furosemide within 7 hours. This furopyridine derivative possesses both antihypertensive and diuretic properties, making it a valuable asset in managing essential hypertension and promoting the elimination of excess fluid from the body.
Originator
Ipsen-Beaufour (United Kingdom)
Check Digit Verification of cas no
The CAS Registry Mumber 82747-56-6 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 8,2,7,4 and 7 respectively; the second part has 2 digits, 5 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 82747-56:
(7*8)+(6*2)+(5*7)+(4*4)+(3*7)+(2*5)+(1*6)=156
156 % 10 = 6
So 82747-56-6 is a valid CAS Registry Number.
InChI:InChI=1/C14H12ClNO2.ClH/c1-8-13(17)12-7-18-14(11(12)6-16-8)9-2-4-10(15)5-3-9;/h2-6,14,17H,7H2,1H3;1H