82748-54-7Relevant articles and documents
Synthesis of novel D-α-galactopyranosyl-L-seryl/L-threonyl-L-alanyl-L-alanine as useful precursors of new glycopeptide antibiotics with computational calculations studies
Khodair, Ahmed I.,Kassab, Shaymaa E.,Kheder, Nabila A.,Fahim, Asmaa M.
, (2022/04/03)
New, simple, synthetic routes for the preparation of novel glycopeptide antibiotics are described. The structures of the synthesized compounds are elucidated by IR, two-dimensional NMR spectroscopy, and mass spectrometry. The stability of the new glycopep
The synthesis of pure Amadori rearrangement products
Noomen, S. N.,Breel, G. J.,Winkel, C.
, p. 321 - 324 (2007/10/02)
The term "Maillard reaction" is used to describe a complex set of reactions in foods leading to flavour generation and non-enzymatic browning.The first step in this process is the so-called Amadori rearrangement: a reducing saccharide and a peptide fragment react to form an Amadori Rearrangement Product (ARP).To be able to do model studies on flavour generation, gram amounts of pure ARP are required.In the present study, glucose-derived ARPs were synthesised from specifically protected and activated starting compounds.After deprotection and purification, pure ARPs were obtained.This is the first time that ARPs of dipeptides have been isolated.
[Asn2 ]-thymosin α1 and analogs thereof
-
, (2008/06/13)
Thymosin α1, was chemically synthesized by the fragment condensation of the protected amino terminal tetradecapeptide with the protected carboxyl terminal tetradecapeptide. Similarly prepared was the analog [Asn2 ]-thymosin α1 utilizing the appropriately modified protected amino terminal tetradecapeptide. Both products are active as agents which affect regulation, differentiation and function of thymus dependent lymphocytes (T cells).