82760-84-7 Usage
Uses
Used in Pharmaceutical and Medicinal Chemistry:
N-Methyl-N-phenyl-9H-purin-6-amine is utilized as a potential active pharmaceutical ingredient due to its structural resemblance to established purine-based drugs. Its unique chemical properties may contribute to the development of new therapeutic agents with novel mechanisms of action.
Used in Drug Development Research:
N-Methyl-N-phenyl-9H-purin-6-amine serves as a valuable research tool in drug development, aiding scientists in understanding the interactions between purine-based compounds and biological targets. Its unique structure can provide insights into the design of new drugs with improved efficacy and selectivity.
Used in Biological Studies:
N-Methyl-N-phenyl-9H-purin-6-amine is employed in biological studies to explore its interactions with cellular components and its potential effects on biological processes. This can lead to a better understanding of purine metabolism and its role in various physiological and pathological conditions.
Check Digit Verification of cas no
The CAS Registry Mumber 82760-84-7 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 8,2,7,6 and 0 respectively; the second part has 2 digits, 8 and 4 respectively.
Calculate Digit Verification of CAS Registry Number 82760-84:
(7*8)+(6*2)+(5*7)+(4*6)+(3*0)+(2*8)+(1*4)=147
147 % 10 = 7
So 82760-84-7 is a valid CAS Registry Number.
InChI:InChI=1/C12H11N5/c1-17(9-5-3-2-4-6-9)12-10-11(14-7-13-10)15-8-16-12/h2-8,10H,1H3
82760-84-7Relevant academic research and scientific papers
Myers, Michael R.,Setzer, Natalie N.,Spada, Alfred P.,Persons, Paul E.,Ly, Cuong Q.,Maguire, Martin P.,Zulli, Allison L.,Cheney, Daniel L.,Zilberstein, Asher,Johnson, Susan E.,Franks, Carol F.,Mitchell, Karen J.
, p. 421 - 424 (1997)
We have identified moderately potent and selective inhibitors of CSF-1R tyrosine kinase activity. A preliminary SAR study resulted in the identification of compounds 11 and 20 as the most potent analogues in the series (IC50 - 0.18 μM). The 3-D-conformation of the 4-(N-alkyl-N-phenyl)-aminoquinazolines has been proposed to be important to the overall selectivity and activity.
