82766-13-0

Basic information

• Product Name: Phenyl(2-pyridyl)methanonethiosemicarbazone
• Synonyms: 2-(Phenyl-2-pyridinylmethylene)-1-hydrazinecarbothioamide;2-Benzoylpyridine thiosemicarbazone;2-Pyridylphenyl ketonethiosemicarbazone;Phenyl 2-pyridyl ketone thiosemicarbazone;Phenyl(2-pyridinyl)methanonethiosemicarbazone;Phenyl(2-pyridyl)methanonethiosemicarbazone
• CAS NO: 82766-13-0
• Molecular Formula: C₁₃H₁₂N₄S
• Molecular Weight: 0
• Mol File: 82766-13-0.mol
• Article Data: 11

Chemical Properties

• Boiling Point: 436.9°C at 760 mmHg
• Flash Point: 218°C
• Appearance: /
• Density: 1.25g/cm³
• Vapor Pressure: 7.82E-08mmHg at 25°C
• Refractive Index: 1.662
• CAS DataBase Reference: Phenyl(2-pyridyl)methanonethiosemicarbazone(CAS DataBase Reference)
• NIST Chemistry Reference: Phenyl(2-pyridyl)methanonethiosemicarbazone(82766-13-0)
• EPA Substance Registry System: Phenyl(2-pyridyl)methanonethiosemicarbazone(82766-13-0)

Safety Data

• Hazardous Substances Data: 82766-13-0(Hazardous Substances Data)

Usage

General Description

Phenyl(2-pyridyl)methanonethiosemicarbazone, also known as PPMTSC, is a chemical compound with potential anticancer and antiviral properties. It has been studied for its ability to inhibit the growth of cancer cells and has shown promising results in preclinical studies. PPMTSC has also demonstrated antiviral activity against certain viruses, making it a potential candidate for the development of new antiviral drugs. Additionally, it has been investigated for its potential use in the treatment of neurodegenerative disorders, as it has shown neuroprotective effects in experimental models. Overall, Phenyl(2-pyridyl)methanonethiosemicarbazone shows potential as a versatile compound with various therapeutic applications.

InChI:InChI=1/C13H12N4S/c14-13(18)17-16-12(10-6-2-1-3-7-10)11-8-4-5-9-15-11/h1-9H,(H3,14,17,18)

Upstream product

• 91-02-1 phenyl(pyridin-2-yl)methanone 
• 79-19-6 thiosemicarbazide 

Relevant articles and documents

Novel biotin-functionalized lipidic nanocarriers for encapsulating BpT and Bp4eT iron chelators: Evaluation of potential anti-tumour efficacy by: In vitro, in vivo and pharmacokinetic studies in A549 mice models

Tumour cells have a high demand for iron (Fe) due to their rapid rate of proliferation. Strategies to target intracellular iron for antitumour therapy have not been systematically explored. The benzoylpyridine thiosemicarbazone (BpT) group of Fe-binding d

Platinum complex taking 2-benzoylpyridine thiosemicarbazone as ligand as well as synthesis method and application of platinum complex

The invention discloses a thiosemicarbazone platinum complex taking 2-benzoyl pyridine as a ligand as well as a synthesis method and application of the thiosemicarbazone platinum complex. 2-benzoyl pyridine and thiosemicarbazone are selected for condensat

Gallium(iii)-2-benzoylpyridine-thiosemicarbazone complexes promote apoptosis through Ca2+ signaling and ROS-mediated mitochondrial pathways

Ga(iii) compounds are highly promising candidates for antitumor therapy. The level of intracellular reactive oxygen species (ROS) is significantly increased after Ga(iii) complex treatment, but these complexes are redox-inactive. To investigate the effect