82781-81-5

Basic information

• Product Name: methyl 7-(5-acetyl-4,5-dihydro-1,2-oxazol-3-yl)heptanoate
• CAS NO: 82781-81-5
• Molecular Formula: C₁₃H₂₁NO₄
• Molecular Weight: 255.3101
• Mol File: 82781-81-5.mol
• Article Data: 1

Chemical Properties

• Boiling Point: 351.8°C at 760 mmHg
• Flash Point: 141.1°C
• Density: 1.14g/cm³
• Vapor Pressure: 4E-05mmHg at 25°C
• Refractive Index: 1.51
• CAS DataBase Reference: methyl 7-(5-acetyl-4,5-dihydro-1,2-oxazol-3-yl)heptanoate(CAS DataBase Reference)
• NIST Chemistry Reference: methyl 7-(5-acetyl-4,5-dihydro-1,2-oxazol-3-yl)heptanoate(82781-81-5)
• EPA Substance Registry System: methyl 7-(5-acetyl-4,5-dihydro-1,2-oxazol-3-yl)heptanoate(82781-81-5)

Safety Data

• Hazardous Substances Data: 82781-81-5(Hazardous Substances Data)

Upstream product

• 82781-91-7 butyl 8-nitrooctanoate 
• 502-49-8 cycloactanone 
• 59080-48-7 methyl 8-nitrooctanoate 

Relevant articles and documents

Silyl Nitronates in Organic Synthesis. Routes to Heterocycles and Cyclopentanoids. Synthesis of Allethrolone and Calythrone. Acylation and Cyanohydroxylation of Double Bonds. An Exploratory Study

Silyl nitronates are versatile reagents for the preparation of heterocycles by dipolar addition to double bonds.The intermediate isoxazolidines can be transformed to 2-isoxazolines, isoxazoles, furans, dihydrofuranones, pyrazoles, pyridazines and pyridazones.Reduction of 2-isoxazolines with Ti3+ leads to hydroxylated 1,4-diketones, which subsequently can be cyclized to cyclopentenones.Routes to calythrone, rethrolones, prostanoids and a number of naturally occurring dihydrofuranones are devised, as well as synthetic procedures for acylation, preparation of endiones, hydroxyacylation, cyanation and hydroxycyanation of double bonds.