82782-27-2Relevant articles and documents
Visible light mediated metal-free thiol-yne click reaction
Zalesskiy, Sergey S.,Shlapakov, Nikita S.,Ananikov, Valentine P.
, p. 6740 - 6745 (2016)
The carbon-sulfur bond formation reaction is of paramount importance for functionalized materials design, as well as for biochemical applications. The use of expensive metal-based catalysts and the consequent contamination with trace metal impurities are challenging drawbacks of the existing methodologies. Here, we describe the first environmentally friendly metal-free photoredox pathway to the thiol-yne click reaction. Using Eosin Y as a cheap and readily available catalyst, C-S coupling products were obtained in high yields (up to 91%) and excellent selectivity (up to 60:1). A 3D-printed photoreactor was developed to create arrays of parallel reactions with temperature stabilization to improve the performance of the catalytic system.
DIRECTION OF NUCLEOPHILIC ADDITION OF ARENETHIOLS TO ACETYLENIC ALCOHOLS
Dzhafarov, A. A.,Aslanov, I. A.,Trofimov, B. A.,Ibadzade, A. K.,Ibragimov, N. Yu.
, p. 643 - 646 (2007/10/02)
2-Arylthio-2-propen-1-ols and 3-arylthio-2-propen-1-ols (E and Z isomers),i.e., the products from addition according to and against the Markovnikov rule, were synthesized by the reaction of arenethiols with acetylenic alcohols.The prototropic rearrangemen
