82788-50-9

Upstream product

• 82788-00-9 6-(hydroxymethyl)-4-methoxybenzothiophene-2-carboxylic acid methyl ester 
• 82788-01-0 6-(chloromethyl)-4-methoxybenzothiophene-2-carboxylic acid methyl ester 
• 82787-99-3 6-hydroxymethyl-4-methoxybenzo[b]thiophene-2-carboxylic acid 
• 82788-02-1 6-(1-imidazolylmethyl)-4-methoxybenzo[b]-thiophene-2-carboxylic acid methyl ester 

Relevant academic research and scientific papers

Heterocyclic thromboxane synthetase inhibitors and pharmaceutical compositions containing them

Heterocyclic thromboxane synthetase inhibitors of the formula STR1 wherein R1, which is attached to the 2-, 3- or 4-position, is hydrogen, halogen, C1 -C4 alkyl, hydroxy or C1 -C4 alkoxy; Y, which is attached to the 2- or 3-position, is --COOH, --COO(C1 -C4 alkyl) or --CONH2 ; X is O, S, NH, N(C1 -C4 alkyl) or N(benzyl); and R, which is attached to the 5-, 6- or 7-position, is a group of the formula STR2 or (3- or 4-pyridyl)-Z2 - wherein Z1 is --CH2 --, --CH2 CH2 -- or --CH2 CH2 O-- and Z2 is --CH2 --, --CH2 CH2 --, --CH=CH--, --CH2 O-- or --OCH2 --; and their pharmaceutically acceptable salts; processes for their preparation, and pharmaceutical compositions containing them.