82790-29-2Relevant academic research and scientific papers
Synthesis, characterization, and cytotoxic activity of tricyclohexyltin(IV) carboxylates derived from cyclic dicarboxylic anhydrides
Tian, Laijin,Cao, Hui,Wang, Shouxin,Sun, Yuxi,Liu, Zhi
, p. 624 - 637 (2013/06/05)
Some tricyclohexyltin(IV) carboxylates, HOOC-R-COOSn(c-C6H 11)3 (1) and (c-C6H11) 3SnOOC-R-COOSn(c-C6H11)3 (2) [R = 1,2-C6H4 (a), 1,2-C6F4 (b), (Z)-CH=CH (c), CH2CH2 (d)], have been synthesized from reaction of tricyclohexyltin hydroxide with cyclic dicarboxylic anhydrides under microwave irradiation in 1: 1 and 2: 1 M ratio, respectively, and characterized by elemental analysis, IR and NMR (1H, 13C, and 119Sn) spectra. Crystal structures of 1a-1c and 2d are determined by X-ray single crystal diffraction. The carboxylate in each compound is monodentate to tin. Compounds 1a and 1c possess a trans-C3SnO 2 trigonal bipyramidal geometry with axial positions occupied by carboxylate and carbonyl oxygen of carboxylate of an adjacent molecule forming a one-dimensional chain. Compound 1b is tetrahedral and forms R 2 2(8) hydrogen-bonded dimers by pairs of intermolecular O-H O hydrogen bonds between two carboxylic acid groups. Compound 2d is dinuclear with tin possessing distorted tetrahedral geometry; a trimer supramolecular structure is formed by weak intermolecular Sn O interactions. The compounds have potent in vitro cytotoxic activity against two human tumor cell lines, A549 and HeLa.
Preparation, spectroscopic studies and structure of bis(triorganostannyl) esters of substituted aliphatic dicarboxylic acids
Samuel-Lewis, Areila,Smith, Peter J.,Aupers, John H.,Hampson, David,Povey, David C.
, p. 131 - 144 (2007/10/02)
Bis(triorganostannyl) esters of phenylmaleic acid, citraconic acid, maleic acid, phenylsuccinic acid, methylsuccinic acid and succinic acid, R3SnO2CCR1:CHCO2SnR3 (R=Bu, Ph, Cy; R1=Ph, Me, H) and R3SnO2CCHR1*CH2CO2SnR3 (R=Bu, Ph; R1=Ph and R=Bu, Ph, Cy; R1=Me, H), have been prepared from R3SnOH or (Bu3Sn)2O and the dicarboxylic acid or its anhydride.The structures of these compounds in the solid state are discussed with reference to their IR and Moessbauer spectra.The crystal structures of the bis(triphenylstannyl) esters of phenylmaleic acid and citraconicacid have been determined by single crystal X-ray diffraction.In the first diester, both tin atoms are occupying tetrahedral geometries, with no short intermolecular O...Sn contacts.In bis(triphenyltin) citraconate, the carboxylatotin attached to the substituted olefinic carbon is also four coordinate, but the second tin atom is five coordinate, due to intermolecular coordination by a carboxylate group from a neighbouring molecule , thereby giving rise to a polymeric chain structure.The tributylstannyl monoester of citraconic acid has been synthesized and its structure in solution assigned by 13C and 119Sn NMR spectroscopy and, in the solid state, by IR and Moessbauer spectroscopy.
