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82791-48-8

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82791-48-8 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 82791-48-8 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 8,2,7,9 and 1 respectively; the second part has 2 digits, 4 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 82791-48:
(7*8)+(6*2)+(5*7)+(4*9)+(3*1)+(2*4)+(1*8)=158
158 % 10 = 8
So 82791-48-8 is a valid CAS Registry Number.

82791-48-8Downstream Products

82791-48-8Relevant articles and documents

Chemoenzymatic synthesis and biological evaluation of 2- and 3-hydroxypyridine derivatives against Leishmania mexicana

Garcia Linares, Guadalupe,Parraud, Gonzalo,Labriola, Carlos,Baldessari, Alicia

experimental part, p. 4614 - 4624 (2012/09/05)

A series of hydroxyalkyl and acyloxyalkyl derivatives of 2- and 3-hydroxypyridine was synthesized and their biological activity was evaluated as growth inhibitors of protozoan Leishmania mexicana. Thirty novel compounds were obtained through a chemoenzymatic methodology in two reaction steps. The influence of various reaction parameters in the enzymatic step, such as enzyme source, acylating agent/substrate ratio, enzyme/substrate ratio, solvent and temperature, was studied. Some of the evaluated compounds showed a remarkable activity as Leishmania mexicana growth inhibitors, obtaining the best results with the acetylated derivatives. The advantages showed by the enzymatic methodology, such as mild reaction conditions and low environmental impact, make the biocatalysis a convenient way to prepare these derivatives of substituted pyridines with application as potential antiparasitic agents.

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