82818-61-9Relevant academic research and scientific papers
Inert Carbon Free Radicals. 4. Spin Labeling of Amino Acids and Peptides
Ballester, M.,Riera, J.,Castaner, J.,Rovira, C.,Veciana, J.,Onrubia, C.
, p. 3716 - 3720 (2007/10/02)
The first examples of spin labeling with inert free-radical reagents are presented.Those here described involve tagging of amino acids and peptides, the labeling reagents being tetradecachloro-4-(chlorocarbonyl)triphenylmethyl(2), 4-aminotetradecachlorotr
AN ABNORMAL HYDROLYTIC C-N CLEAVAGE OF THE AMIDE GROUP IN N-SUBSTITUTED 4-CARBAMOYLTETRADECACHLOROTRIPHENYLMETHYL RADICALS, AND RELATED REACTIONS
Ballester, M.,Riera, J.,Castaner, J.,Onrubia, C.,Ubierna, J. J.
, p. 2121 - 2124 (2007/10/02)
The alkaline hydrolysis of amides p-(RCH2NHCO)-C6Cl4-C(C6Cl5)2 (R, CO2Et or CO2H) occurs via methylene-nitrogen bond cleavage.Under the given conditions, the amide group in the corresponding non-radical, triarylmethane species, and in 4-(benzylcarbamoyl)tetradecachlorotriphenylmethyl radical, does not undergo any hydrolysis.That abnormal cleavage is traced therefore to the radical character.
