828247-82-1 Usage
Uses
Used in Pharmaceutical Research:
Uridine, 5'-O-[bis(4-methoxyphenyl)phenylmethyl]-2'-O-[1-(2-cyanoethoxy)ethyl]is used as a research compound for investigating the effects of chemical modifications on nucleosides. Its unique structure allows scientists to explore how these modifications impact the compound's interaction with biological systems and its potential therapeutic applications.
Used in Drug Development:
In the pharmaceutical industry, this modified uridine may be used as a lead compound for the development of new drugs targeting specific cellular functions. Its ability to modulate RNA and DNA synthesis, neurotransmission, and metabolism could be harnessed to create treatments for various diseases and conditions.
Used in Biochemical Studies:
Uridine, 5'-O-[bis(4-methoxyphenyl)phenylmethyl]-2'-O-[1-(2-cyanoethoxy)ethyl]is used as a biochemical tool to study the mechanisms of nucleoside incorporation and metabolism within cells. Understanding these processes can provide insights into the fundamental biology of cells and contribute to the development of novel therapeutic strategies.
Used in Neurotransmission Research:
Given its potential impact on neurotransmission, this modified uridine may be used in research aimed at understanding and treating neurological disorders. Its unique structure could offer new avenues for modulating neurotransmitter levels and signaling pathways, leading to improved treatments for conditions such as epilepsy, Parkinson's disease, and Alzheimer's disease.
Used in Metabolic Research:
Uridine, 5'-O-[bis(4-methoxyphenyl)phenylmethyl]-2'-O-[1-(2-cyanoethoxy)ethyl]is used as a research tool in metabolic studies, where it can help elucidate the role of nucleosides in cellular metabolism and energy production. This knowledge can contribute to the development of therapies for metabolic disorders and conditions related to energy imbalances.
Check Digit Verification of cas no
The CAS Registry Mumber 828247-82-1 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 8,2,8,2,4 and 7 respectively; the second part has 2 digits, 8 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 828247-82:
(8*8)+(7*2)+(6*8)+(5*2)+(4*4)+(3*7)+(2*8)+(1*2)=191
191 % 10 = 1
So 828247-82-1 is a valid CAS Registry Number.
828247-82-1Relevant academic research and scientific papers
Oligoribonucleotide synthesis by the use of 1-(2-cyanoethoxy)ethyl (CEE) as a 2′-hydroxy protecting group
Umemoto, Tadashi,Wada, Takeshi
, p. 9529 - 9531 (2007/10/03)
A novel method for the synthesis of oligoribonucleotide using 1-(2-cyanoethoxy)ethyl (CEE) as a 2′-hydroxy protecting group has been developed. A novel method for the synthesis of oligoribonucleotides using 1-(2-cyanoethoxy)ethyl (CEE) as a 2′-hydroxy protecting group has been developed. A CEE group was introduced to the 2′-position of N-acyl-3′,5′-O-silyl-protected ribonucleosides under acidic conditions in good yields. The 2′-O-CEE group was found to be stable in an aqueous or ethanolic ammonia and was quickly removed by treatment with anhydrous tetrabutylammonium fluoride (TBAF). A combination of the use of N-acyl and 2′-O-CEE protecting groups enabled a reliable and complete two-step deprotection, first with NH3-EtOH, then with TBAF in THF, without cleavage of internucleotidic linkages.
