82826-58-2Relevant academic research and scientific papers
Carbonyldiimidazole-mediated lossen rearrangement
Dube, Pascal,Fine Nathel, Noah F.,Vetelino, Michael,Couturier, Michel,Aboussafy, Claude Larrivee,Pichette, Simon,Jorgensen, Matthew L.,Hardink, Mark
supporting information; body text, p. 5622 - 5625 (2010/03/02)
[Chemical Equation Presented] Carbonyldiimidazole (CDI) was found to mediate the Lossen rearrangement of various hydroxamic acids to isocyanates. This process is experimentally simple and mild, with imidazole and CO 2 being the sole stoichiometric byproduct. Significant for large-scale application, the method avoids the use of hazardous reagents and thus represents a green alternative to standard processing conditions for the Curtius and Hofmann rearrangements.
SYNTHESIS OF ARYLALKYLHYDROXAMIC ACIDS WITH AN α-ASYMMETRICAL CARBON ATOM
Potapov, V. M.,Dem'yanovich, V. M,Vendrova, O. E.,Khlebnikov, V. A.
, p. 1041 - 1043 (2007/10/02)
Optically active hydroxamic acids have been obtained by two routes from (-)-2-phenylpropanoic, (-)-2-methyl-3-phenylpropanoic, and (-)-2-methyl-4-phenylbutanoic acids.It has been shown that the hydroxamic acids obtained by reaction of the acids with hydro
