828265-17-4Relevant academic research and scientific papers
The preparation of new phosphorus-centered functional groups for modified oligonucleotides and other natural phosphates
Gautier, Arnaud,Lopin, Chrystel,Garipova, Goulnara,Dubert, Olivier,Kalinina, Irina,Salcedo, Carmen,Balieu, Sebastien,Glatigny, Stephane,Valnot, Jean-Yves,Gouhier, Geraldine,Piettre, Serge R.
, p. 1048 - 1073 (2005)
Efforts to develop synthetic methodologies allowing the preparation of α,α-difluorophosphonothioates, α,α- difluorophosphonodithioates, α,α-difluorophosphonotrithioates, and α,α-difluorophosphinates are reviewed in the light of applications in the field o
α,α-difluoro-H-phosphinates: Useful intermediates for a variety of phosphate isosteres
Gautier, Arnaud,Garipova, Goulnara,Salcedo, Carmen,Balieu, Sebastien,Piettre, Serge R.
, p. 5963 - 5967 (2007/10/03)
Addition of the radical generated from the sodium salt of hypophosphorous acid to difluoroalkenes results in the formation of α,α-difluoro-H- phosphinates. These intermediates can be transformed into different phosphorus-centered isosteres, such as difluo
