82830-27-1

Basic information

• Product Name: Acetic acid, [5-[(2,4-diamino-5-pyrimidinyl)methyl]-2,3-dimethoxyphenoxy]-, methyl ester
• CAS NO: 82830-27-1
• Molecular Formula: C16H20N4O5
• Molecular Weight: 348.359
• Mol File: 82830-27-1.mol

Chemical Properties

• CAS DataBase Reference: Acetic acid, [5-[(2,4-diamino-5-pyrimidinyl)methyl]-2,3-dimethoxyphenoxy]-, methyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: Acetic acid, [5-[(2,4-diamino-5-pyrimidinyl)methyl]-2,3-dimethoxyphenoxy]-, methyl ester(82830-27-1)
• EPA Substance Registry System: Acetic acid, [5-[(2,4-diamino-5-pyrimidinyl)methyl]-2,3-dimethoxyphenoxy]-, methyl ester(82830-27-1)

Safety Data

• Hazardous Substances Data: 82830-27-1(Hazardous Substances Data)

Upstream product

• 96-32-2 bromoacetic acid methyl ester 
• 27653-69-6 2,4-diamino-<3,4-dimethoxy-5-hydroxybenzyl>pyrimidine 

Downstream Products

• 82830-22-6 [5-(2,4-Diamino-pyrimidin-5-ylmethyl)-2,3-dimethoxy-phenoxy]-acetic acid 

Relevant articles and documents

Receptor-based design of dihydrofolate reductase inhibitors: Comparison of crystallographically determined enzyme binding with enzyme affinity in a series of carboxy-substituted trimethoprim analogues

By the use of molecular models of Escherichia coli dihydrofolate reductase (DHFR), analogues of trimethoprim (TMP) were designed which incorporated various 3'-carboxyalkoxy moieties in order to acquire ionic interactions with positively charged active-sit