82831-19-4

Basic information

• Product Name: ETHYL 5-METHYL-2-OXO-1H,3H-IMIDAZOLIN-4-CARBOXYLATE
• Synonyms: ETHYL 5-METHYL-2-OXO-1H,3H-IMIDAZOLIN-4-CARBOXYLATE;ethyl 5-methyl-2-oxo-2,3-dihydro-1H-imidazole-4-carboxylate;ethyl 4-methyl-2-oxo-2,3-dihydro-1H-imidazole-5-carboxylate
• CAS NO: 82831-19-4
• Molecular Formula: C₇H₁₀N₂O₃
• Molecular Weight: 170.17
• Mol File: 82831-19-4.mol
• Article Data: 1

Chemical Properties

• Melting Point: 224-225 °C
• Appearance: /
• Density: 1.209g/cm³
• Refractive Index: 1.488
• PKA: 10.70±0.70(Predicted)
• CAS DataBase Reference: ETHYL 5-METHYL-2-OXO-1H,3H-IMIDAZOLIN-4-CARBOXYLATE(CAS DataBase Reference)
• NIST Chemistry Reference: ETHYL 5-METHYL-2-OXO-1H,3H-IMIDAZOLIN-4-CARBOXYLATE(82831-19-4)
• EPA Substance Registry System: ETHYL 5-METHYL-2-OXO-1H,3H-IMIDAZOLIN-4-CARBOXYLATE(82831-19-4)

Safety Data

• Hazardous Substances Data: 82831-19-4(Hazardous Substances Data)

Usage

Synthesis Reference(s)

Journal of the American Chemical Society, 67, p. 2079, 1945 DOI: 10.1021/ja01228a008

InChI:InChI=1/C7H10N2O3/c1-3-12-6(10)5-4(2)8-7(11)9-5/h3H2,1-2H3,(H2,8,9,11)

Upstream product

• 18632-42-3 2-acetoxy-acetoacetic acid ethyl ester 
• 62909-23-3 4-ethoxy-2-hydroxyimino-3-oxo-butyric acid ethyl ester 
• 41051-14-3 ethyl 4-ethoxy-3-oxobutanoate 
• 590-28-3 potassium cyanate 
• 5408-04-8 ethyl 2-hydroxyimino-3-oxobutanoate 
• 57-13-6 urea 
• 609-15-4 ethyl 2-chloro-3-oxo-butyrate 
• 15863-59-9 2-Hydroxy-3-oxo-buttersaeure-ethylester 
• 874531-79-0 5-ethoxymethyl-2-oxo-2,3-dihydro-1H-imidazole-4-carboxylic acid ethyl ester 

Downstream Products

• 6531-31-3 4-methyl-imidazolidin-2-one 
• 1192-34-3 4-methyl-1,3-dihydro-imidazol-2-one 

Relevant articles and documents

Cardiotonic imidazolecarboxylic acid derivatives

The use of novel imidazolecarboxylic acid derivatives of the following general structure which are useful as antihypertensives, cardiotonics and antithrombotics STR1 wherein Q and T are an oxygen or sulfur atom; R is hydrogen, lower alkyl, lower alkylcarbonyl or benzoyl; R1 is hydrogen or --CH(R3)R4 ; R2 is lower alkoxy, phenoxy or phenoxy substituted at the ortho, meta, or para position with lower alkyl, lower alkoxy, hydroxy, halogen, trifluoromethyl, lower alkylthio, lower alkylsulfone, or lower alkylsulfoxide; R3 is hydrogen or lower alkyl; R4 is hydrogen, hydroxy, lower alkoxy, lower alkylcarbonyl, --ONO2 or halogen; and their pharmaceutically acceptable salts thereof.