82843-16-1

Basic information

• Product Name: 2-hydroxy-3-propanoyl-4H-chromen-4-one
• CAS NO: 82843-16-1
• Molecular Formula: C₁₂H₁₀O₄
• Molecular Weight: 218.2054
• Mol File: 82843-16-1.mol
• Article Data: 2

Chemical Properties

• Boiling Point: 353.9°C at 760 mmHg
• Flash Point: 138.1°C
• Density: 1.382g/cm³
• Vapor Pressure: 1.28E-05mmHg at 25°C
• Refractive Index: 1.616
• CAS DataBase Reference: 2-hydroxy-3-propanoyl-4H-chromen-4-one(CAS DataBase Reference)
• NIST Chemistry Reference: 2-hydroxy-3-propanoyl-4H-chromen-4-one(82843-16-1)
• EPA Substance Registry System: 2-hydroxy-3-propanoyl-4H-chromen-4-one(82843-16-1)

Safety Data

• Hazardous Substances Data: 82843-16-1(Hazardous Substances Data)

Upstream product

• 78-81-9 isobutylamine 
• 88518-16-5 6-Ethyl-5,7-dihydroxy-2,2-dimethyl-2H-thiopyrano<2,3-b>pyridin-4(3H)-on 
• 82843-15-0 6-Ethyl-4-isobutylimino-5-hydroxy-2,2-dimethyl-3,4-dihydro-2H-thiopyrano<2,3-b>pyridin-5,7-diol 
• 15781-72-3 bis(2,4,6-trichlorophenyl) ethylmalonate 
• 58913-40-9 4-isobutylamino-6,6-dimethyl-5,6-dihydro-1H-pyridine-2-thione 

Relevant articles and documents

Chemistry of 5,7-Dihydroxy-2H-thiopyranopyridine-4(3H)-one

Hydrolysis of the 4-alkyliminothiopyranopyridinedioles (5) and 4-alkylaminothiopyranopyridones (6) resp. with 10 percent NaOH gives 5,7-dihydroxy-2H-thiopyranopyridine-4(3H)-one (7). 7 can be obtained in better yield by reaction of 4-dimethylamino-2(1H)-pyridinethione (8) with bis-trichlorphenylethylmalonate (2).Aminolysis of 7 affords the two isomeric products 5 and 6.On treatment with hydrazines, 7 reacts only to 4-hydrazono-derivatives 5.By heating in bromobenzene 5d is cyclized to 1H-5,1,2,6-thiatriaza-acenaphthylen-7-ol (11).On methylation with methyliodide 5, 6 and 7 furnish the 7-methoxyproducts 13, 14 and 12.By heating in 20 percent NaOH 7 is transformed into the 2-thioxo-3-pyridylmethylketone 16A and its tautomer, 2-mercapto-3-pyridylmethylketone 16B.The structures of 5, 6 and 7 are discussed. - keywords: 4-Alkylaminothiopyranopyridones; 4-Alkyliminothiopyranopyridindioles; 5,7-Dihydroxy-2H-thiopyranopyridine-4(3H)-one; 2-Mercapto-3-pyridinylmethylketone; 1H-5,1,2,6-Thiatriaza-acenaphthylene; 2-Thioxo-3-pyridylmethylketone