82854-37-3 Usage
Description
Echinacoside is a phenylethanoid glycoside that has been found in Echinacea and has diverse biological activities. It scavenges 2,2-diphenyl-1-picrylhydrazyl (DPPH; ) radicals (EC50 = 6.6 μM in a cell-free assay). Echinacoside (10 μg/ml) inhibits hydrogen peroxide-induced production of reactive oxygen species (ROS) and apoptosis in PC12 cells. It reduces increases in plasma alanine aminotransferase (ALT), TNF-α, IL-1β, IL-16, and IL-10 levels and hepatocyte apoptosis induced by LPS/D-galactosamine in a mouse model of acute liver injury when administered at a dose of 60 mg/kg. Echinacoside (20 mg/kg per day for 15 days) prevents loss of dopaminergic neurons in the substantia nigra pars compacta and decreases in striatal dopamine and 3,4-dihydroxyphenylacetic acid (DOPAC) levels in a mouse model of MPTP-induced Parkinson''s disease. It also improves motor performance in the rotarod test in the same model.
Chemical Properties
White powder
Uses
Echinacoside Ethanolate is a caffeic acid glycoside, known for its neuroprotective, antiinflammatory and anti-oxidative activities. Also an anti[proliferative towards hypoxia influenced pulmonary artery smooth muscle cells.
Check Digit Verification of cas no
The CAS Registry Mumber 82854-37-3 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 8,2,8,5 and 4 respectively; the second part has 2 digits, 3 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 82854-37:
(7*8)+(6*2)+(5*8)+(4*5)+(3*4)+(2*3)+(1*7)=153
153 % 10 = 3
So 82854-37-3 is a valid CAS Registry Number.
