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CAS

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82883-89-4

5,10-bis(uracil-5-ylmethyl)<6-2H1>tetrahydropteroylglutamic acid is a chemical with a specific purpose. Lookchem provides you with multiple data and supplier information of this chemical.

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  • 82883-89-4 Structure

  • Basic information

    1. Product Name: 5,10-bis(uracil-5-ylmethyl)<6-2H1>tetrahydropteroylglutamic acid
    2. Synonyms:
    3. CAS NO:82883-89-4
    4. Molecular Formula:
    5. Molecular Weight: 694.625
    6. EINECS: N/A
    7. Product Categories: N/A
    8. Mol File: 82883-89-4.mol

  • Chemical Properties

    1. Melting Point: N/A
    2. Boiling Point: N/A
    3. Flash Point: N/A
    4. Appearance: N/A
    5. Density: N/A
    6. Refractive Index: N/A
    7. Storage Temp.: N/A
    8. Solubility: N/A
    9. CAS DataBase Reference: 5,10-bis(uracil-5-ylmethyl)<6-2H1>tetrahydropteroylglutamic acid(CAS DataBase Reference)
    10. NIST Chemistry Reference: 5,10-bis(uracil-5-ylmethyl)<6-2H1>tetrahydropteroylglutamic acid(82883-89-4)
    11. EPA Substance Registry System: 5,10-bis(uracil-5-ylmethyl)<6-2H1>tetrahydropteroylglutamic acid(82883-89-4)

  • Safety Data

    1. Hazard Codes: N/A
    2. Statements: N/A
    3. Safety Statements: N/A
    4. WGK Germany:
    5. RTECS:
    6. HazardClass: N/A
    7. PackingGroup: N/A
    8. Hazardous Substances Data: 82883-89-4(Hazardous Substances Data)

82883-89-4 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 82883-89-4 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 8,2,8,8 and 3 respectively; the second part has 2 digits, 8 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 82883-89:
(7*8)+(6*2)+(5*8)+(4*8)+(3*3)+(2*8)+(1*9)=174
174 % 10 = 4
So 82883-89-4 is a valid CAS Registry Number.

82883-89-4Downstream Products

82883-89-4Relevant articles and documents

A Chemical Model for the Thymidylate Synthetase Catalysed Methylation of Deoxyuridine Monophosphate

Charlton, Peter A.,Young, Douglas W.

, p. 1363 - 1370 (2007/10/02)

In a study of a model for the reaction catalysed by the enzyme thymidylate synthetase, a compound previously thought to be the putative intermediate 5-(uracil-5-ylmethyl)tetrahydropteroylglutamic acid (4b) has been prepared and shown to be the 5,10-bis(uracil-5-ylmethyl) adduct (4c).The tetrahydrofolic acid adduct (4d) and its analogue have been prepared and have been shown to be thermally converted into thymine (5, R2=H).The reaction with deuteriated (4d) shows a high discrimination for the hydrogen at C-6 of the pteridine moiety which rearranges to the methyl group of the resultant thymine (5, R2=H).These findings parallel results found for the biochemical process very closely and possible mechanisms for the reaction are discussed.The compounds (4c) and (4d) are neither substrates nor inhibitors of thymidylate synthetase.

Investigation of a Chemical Model for the Methylation of Deoxyuridine Monophosphate by Thymidylate Synthetase

Charlton, Peter A.,Young, Douglas W.

, p. 614 - 616 (2007/10/02)

The compound (4a; R2 = H), long regarded as a putative intermediate in a chemical model for thymine biosynthesis, has been reformulated as the bis-adduct (4b; R2 = H); a chemical model for the action of thymidylate synthetase has been achieved and the result is discussed.

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