82884-90-0

Upstream product

• 80289-65-2 10b,11-epoxy-cis-4b,5,6-10b,11,12-hexahydro-5-methylbenzophenanthridine 
• 80289-65-2 (+)-(4bR,10bS,11R)-10b,11-epoxy-4b,5,6,10b,11,12-hexahydro-5-methylbenzophenanthridine 
• 81370-45-8 (+)-(4bR,10bS,11S)-4b,5,6,10b,11,12-hexahydro-10b,11-dihydroxy-5-methylbenzophenanthridine 
• 77199-05-4 C₁₇H₁₂O₄ 
• 81370-44-7 (+)-(4bR,10bS,11S,12S)-4b,5,6,10b,11,12-hexahydro-10b,11,12-trihydroxy-5-methylbenzophenanthridine 
• 81370-43-6 (+)-(4bR,10bS,11S,12S)-4b,5,6,10b,11,12-hexahydro-10b,11,12-trihydroxy-5-methyl-6-oxobenzophenanthridine 
• 1519-21-7 2-phenylbutyric anhydride 
• 82916-56-1 (+/-)-(2S*,3R*)-1,2,3,4-tetrahydro-3-hydroxynaphthalene-2-spiro-1'-2'-methylisoindoline 

Relevant academic research and scientific papers

Heterocycles. XIII. Syntheses and Absolute Configurations of Chiral Benzophenanthridines

Chiral benzophenanthridines have been synthesized.Aminolysis of the(-)-epoxyhydroxy lactone (3) with methylamine stereospecifically gives the (+)-trihydroxy lactam (5), from which the (+)-10b-hydroxychelidonine (7) and (+)-11-epichelidonine analogs (10) are derived.The absolute configurations of the compounds obtained are assigned on the basis of that of (-)-3 and the results obtained from the subsequent stereocontrolled reactions.The absolute configurations of (+)-7 and (+)-10 are confirmed by Horeau's method.Keywords- chiral benzophenanthridine; absolute configuration; circular dichroism; optical rotatory dispersion; proton magnetic resonance (contact shift)