828916-92-3Relevant academic research and scientific papers
Synthesis and antiviral activities of novel 2′,4′- or 3′,4′-doubly branched carbocyclic nucleosides as potential antiviral agents
Oh, Chang Hyun,Hong, Joon Hee
, p. 457 - 463 (2007/10/03)
In this study, a series of 2′,4-′ or 3′,4′-doubly branched carbocyclic nucleosides (11, 12, 19, and 20) were synthesized from simple acyclic ketone derivatives as starting materials. The installation of the 4′-quaternary carbon needed was carried out usin
Synthesis and biological evaluation of novel 2′,3′,4′- triply branched carbocyclic nucleosides as potential antiviral agents
Ko, Ok Hyun,Hong, Joon Hee
, p. 579 - 586 (2007/10/03)
Novel 2′,3′,4′-triply branched carbocyclic nucleosides were synthesized in this study. The introduction of two methyl groups in the 2′- and 3′-position was accomplished by a Horner-Wadsworth-Emmons reaction and isopropenyl magnesiumbromide addition, respe
