828921-09-1Relevant articles and documents
Light-directed radial combinatorial chemistry: Orthogonal safety-catch protecting groups for the synthesis of small molecule microarrays
Shaginian, Alex,Patel, Madhusudan,Li, Mo-Huang,Flickinger, Shane T.,Kim, Changhan,Cerrina, Franco,Belshaw, Peter J.
, p. 16704 - 16705 (2007/10/03)
We describe the development of photolabile protecting groups based on the 3,4,5-trimethoxyphenacyl group (TMP). Orthogonal safety-catches were created by introducing an acid-activatible dimethyl ketal (AA-TMP) and an oxidatively activatible 1,3-dithiane (