82898-13-3

Usage

Structure

Six-carbon chain with a carboxylic acid group and a double bond at the fourth position

Appearance

Colorless to pale yellow liquid

Odor

Fruity, green, and fatty

Uses

Production of flavors and fragrances for perfumes, soaps, and food products

Biological activities

Potential antifungal and antimicrobial properties, of interest in pharmaceutical research

InChI:InChI=1/C8H14O2/c1-6(2)4-5-7(3)8(9)10/h4,7H,5H2,1-3H3,(H,9,10)

Upstream product

• 4442-06-2 methyl-(3-methyl-but-2-enyl)-malonic acid 
• 609-08-5 Diethyl methylmalonate 
• 870-63-3 prenyl bromide 
• 17063-07-9 diethyl 2-methyl-2-(3-methylbut-2-en-1-yl)malonate 
• 115-18-4 2-methyl-3-buten-2-ol 
• 503-60-6 3,3-dimethyl-allyl chloride 
• 22539-80-6 diethyl (3-methylbut-2-enyl)malonate 
• 261767-57-1 2-methylbut-3-en-2-yl 2-bromopropanoate 

Relevant academic research and scientific papers

Indium-mediated Reformatsky-Claisen rearrangement

A new variant of the Reformatsky-Claisen rearrangement is described. The reaction of substituted allyl α-bromoacetates with indium and indium(III) chloride under ultrasonication provides a general entry into the functionalized synthon.

Azaprostacyclins, their preparation and pharmaceutical use

Azaprostacyclins of Formula I STR1 wherein R1 is hydrogen, alkyl, cycloalkyl, aryl, a heterocyclic residue, or a phenacyl residue optionally substituted on the phenyl ring by bromine, phenyl, alkoxy, or dialkoxy, W is a free or functionally modified carbonyl group or a STR2 wherein R8 is hydrogen or alkyl of 1-5 carbon atoms and R9 is hydrogen or a readily cleavable ether or acyl residue and wherein the OR9 -group can be in the α- or β-position, R2 is a free or functionally modified hydroxy group.