82918-73-8Relevant academic research and scientific papers
General Synthetic Route to γ-Butyrolactones via Stereoselective Radical Cyclization by Organotin Species
Ueno, Yoshio,Moriya, Osamu,Chino, Kunitake,Watanabe, Masaru,Okawara, Makoto
, p. 1351 - 1356 (2007/10/02)
A new method for the preparation of γ-butyrolactones is described in which the key step is the highly stereoselective radical cyclization of bromoacetals to 2-alkoxytetrahydrofurans in the presence of polymeric or low-molecular weight organotin species. 2-Alkoxytetrahydrofurans can be easily converted into γ-butyrolactones by Jones oxidation.
