82923-81-7

Usage

Uses

Used in Pharmaceutical Industry:
(S)-Indoline-2-carboxylic acid ethyl ester is utilized as a building block for the synthesis of various drugs and pharmaceuticals, playing a crucial role in the development of new medicinal compounds.
Used in Research and Development:
In the realm of scientific research, (S)-Indoline-2-carboxylic acid ethyl ester serves as a key component in the exploration and creation of new chemical entities, contributing to the advancement of chemical knowledge and innovation.

InChI:InChI=1/C11H13NO2/c1-2-14-11(13)10-7-8-5-3-4-6-9(8)12-10/h3-6,10,12H,2,7H2,1H3/t10-/m0/s1

Upstream product

• 82950-72-9 1-acetyl-2,3-indoline-2-carboxylic acid 
• 64-17-5 ethanol 
• 79815-20-6 (S)-indoline-2-carboxylic acid 

Downstream Products

• 86323-74-2 ethyl 1-<3-(benzoylthio)-2(S)-methylpropionyl>indoline-2(S)-carboxylate 
• 157521-18-1 (S)-1-[(S)-3-Benzyloxycarbonyl-2-(1,3-dioxo-1,3-dihydro-isoindol-2-yl)-propionyl]-2,3-dihydro-1H-indole-2-carboxylic acid ethyl ester 
• 153391-18-5 (2S,3aS,7aS)-1-((R)-3-Phenyl-4,5-dihydro-isoxazole-5-carbonyl)-octahydro-indole-2-carboxylic acid ethyl ester 
• 78779-29-0 l-(S)-2,3-dihydro-1-[(S)-3-mercapto-2-methyl-1-oxopropyl]-1H-indole-2-carboxylic acid 
• 110660-78-1 (S)-2,3-dihydro-1H-indole-2-carboxamide 
• 208255-26-9 1-[N-(3-nitrophenylacetyl)-L-alaninyl]-indoline-(S)-2-carboxylate ethyl ester 
• 27640-33-1 (2S)-2,3-dihydro-1H-indole-2-ylmethanol 
• 1599453-94-7 (S)-1-((S)-2-tert-butoxycarbonylamino-2-phenylacetyl)-2,3-dihydro-1H-indole-2-carboxylic acid ethyl ester 
• 1599454-03-1 tert-butyl (S)-1-((S)-1-((S)-2-(2,6-difluorophenylcarbamoyl)indolin-1-yl)-3-methyl-1-oxobutan-2-ylamino)-1-oxopropan-2-yl(methyl)carbamate 
• 1599454-00-8 tert-butyl (S)-1-((S)-2-(2,6-difluorophenylcarbamoyl)indolin-1-yl)-3-methyl-1-oxobutan-2-ylcarbamate 
• 166169-39-7 (S)-2-({(S)-1-[(S)-2-((R)-2-tert-Butoxycarbonylamino-3-tritylsulfanyl-propionylamino)-3-methyl-butyryl]-2,3-dihydro-1H-indole-2-carbonyl}-amino)-4-methylsulfanyl-butyric acid tert-butyl ester 

Relevant academic research and scientific papers

COSMETIC USES AND METHODS FOR INDOLINE GRANZYME B INHIBITOR COMPOSITIONS

Cosmetic uses and methods for indoline granzyme B inhibitor compounds in compositions with a cosmetically acceptable carrier. Uses and methods for treating, reducing or inhibiting the appearance of ageing in the skin are provided. Also provided are compositions and formulation for cosmetic uses and methods of maintaining a youthful appearance, reducing an appearance of ageing, inhibiting an appearance of ageing, reducing a rate of an appearance of ageing, reducing a skin inelasticity, reducing a rate of increasing skin inelasticity, maintaining a skin elasticity, and increasing the density of hair follicles of a skin of a subjecl. The uses and methods comprise applying/administering an indoline granzyme B inhibitor to a skin, or a portion of a skin of the subject.

Asymmetric 1,3-dipolar cycloaddition of nitrile oxides to new chiral acrylamides derived from (S)-indoline-2-carboxylic acid

Asymmetric 1,3-dipolar cycloaddition of nitrile oxides to new chiral acrylamides (3a-c) is reported to give the chiral Δ2-isoxazolines with the high diastereoselectivity (up to 95:5).

N-ACYL-gamma-GLUTAMYL IMINO AND AMINO ACIDS AND ESTERS

Compounds of the formula STR1 wherein X is various imino or amino acids or esters are disclosed. These compounds possess angiotensin converting enzyme inhibition activity and depending upon the definition of X also possess enkephalinase inhibition activit

1-mercaptoalkanoylindoline-2-carboxylic acids

1-Mercaptoalkanoylindoline-2-carboxylic acids, e.g., those of the formula STR1 and functional derivatives thereof, are antihypertensive and cardioactive agents.

1-Carboxyalkanoylindoline-2-carboxylic acids

1-Carboxy-(alkanoyl or aralkanoyl)-indoline-2-carboxylic acids, e.g., those of the formula STR1 R=H, alkyl, alkoxy, halogeno or CF3 ; R'=H or R-phenyl; m=0 or 1; p,q=0 to 2; and derivatives thereof, are antihypertensive and cardioactive agents.

1-CARBOXYALKANOYLINDOLINE-2-CARBOXYLIC ACIDS

1-Carboxy-(alkanoyl or aralkanoyl)-indoline-2-carboxylic acids, e.g., those of the formula STR1 R=H, alkyl, alkoxy, halogeno or CF. sub.3 ; R'=H or R-phenyl;m=0 or 1;p, q=0 to 2; and functional derivatives thereof, are antihypertensive a