82953-32-0Relevant articles and documents
THE EFFECT OF TWO ELECTRON-WITHDRAWING GROUPS ON REMOTE TERTIARY HYDROGENS SUSCEPTIBLE TO ELECTROPHILIC FLUORINATION USING F2
Gal, Chava,Rozen, Shlomo
, p. 689 - 694 (1982)
The direct electrophilic fluorination of unactivated remote tertiary hydrogens is effected by the number, natur and distance of electron-withdrawing groups.The effect of these groups on reducing electron density of the tertiary C-H bond seems to be additi
Activating Unreactive Sites of Organic Molecules Using Elemental Fluorine
Rozen, Shlomo,Gal, Chava
, p. 2769 - 2779 (2007/10/02)
Electrophilic substitution reactions on saturated carbons are extremely rare.Elemental fluorine, however, uses this pathway to replace tertiary unactivated hydrogens with great regio- and stereoselectivity, resulting in a full retention of configuration.I