82959-39-5Relevant academic research and scientific papers
Catalyst-Free Sulfonylation of (Hetero)aryl Iodides with Sodium Dithionite
Li, Yuewen,Liu, Tong,Qiu, Guanyinsheng,Wu, Jie
, p. 1154 - 1159 (2019)
The commercially available and cheap sodium dithionite is used as the source of sulfonyl group for the synthesis of sulfones and sulfonamides from (hetero)aryl iodides under catalyst-free conditions. During the reaction process, sodium sulfinates generated in situ are the key intermediate, which can be further converted into diverse sulfones and sulfonamides. This transformation proceeds through a radical process initiated by sodium dithionite, providing a convenient route to sulfonyl-containing compounds. (Figure presented.).
